Dr. Davis attended Ensworth School and Montgomery Bell Academy in Nashville, Tennessee, and graduated summa cum laude from Princeton University (A.B., 1995) with a concentration in African Colonial History. After college, he taught English with Princeton-in-Asia in Hong Kong, and attended Vanderbilt University Medical School (M.D., 2000). From 2000 to 2003, he did internal medicine residency on the Thayer Firm of the Osler Medical Service at Johns Hopkins Hospital. After working at the Kijabe Medical Center in Kenya, he began fellowship in Pulmonary and Critical Care Medicine at UCSF in 2004. In 2008, he completed a Master’s Degree in Clinical Research at UCSF, and joined the faculty of the Division of Pulmonary and Critical Care Medicine at San Francisco General Hospital. Dr. Davis is a member of the Francis J. Curry National Tuberculosis Center and the UCSF Clinical and Translational Sciences Institute K Scholars Program.
Research Interests
My research focuses on improving the diagnosis and management of pulmonary disease in low- and middle-income countries, and is based in Kampala, Uganda, East Africa. There, along with Ugandan colleagues at Mulago Hospital, Makerere University, the National Tuberculosis and Leprosy Programme, and the MU-UCSF Research Collaboration (www.muucsf.org), we are focused on developing and testing new strategies for diagnosing and monitoring HIV-infected patients with tuberculosis (TB). Ongoing studies in a variety of settings are evaluating the diagnostic accuracy, clinical effectiveness, and/or public health impact of novel applications of smear microscopy, culture, nucleic acid testing, and T-cell-based interferon-gamma-release assays for TB diagnosis and management. Future studies will explore how advances in TB diagnostics can be broadly and effectively implemented in high-incidence settings, using a variety of research approaches, including systematic reviews, mathematical modeling, cost-effectiveness analysis, and qualitative methods.
Recent Publications
Davis JL, Welsh DA, Beard CB, Jones JL, Lawrence GG, Fox MR, Crothers K, Morris A, Charbonnet D, Swartzman A, and Huang L. Pneumocystis colonisation is common among hospitalised HIV infected patients with non-Pneumocystis pneumonia. Thorax. 63: 329-34, 2008.
Davis JL, Morris A, Kallet RH, Powell K, Chi AS, Bensley M, Luce JM, and Huang L. Low tidal volume ventilation is associated with reduced mortality in HIV-infected patients with acute lung injury. Thorax. 63: 988-93, 2008.
Cattamanchi A, Davis JL, Worodria W, Yoo S, Matovu J, Kiidha J, Nankya F, Kyeyune R, Andama A, Joloba M, Osmond D, Hopewell P, and Huang L. Poor performance of universal sample processing method for diagnosis of pulmonary tuberculosis by smear microscopy and culture in Uganda. J Clin Microbiol. 46: 3325-9, 2008.
Powell K, Davis JL, Morris AM, Chi A, Bensley MR, Huang L. Survival for patients with HIV admitted to the ICU continues to improve in the current era of combination antiretroviral therapy. Chest. 135: 11-7, 2009.
Davis JL, Huang L, Kovacs JA, Masur H, Murray P, Havlir DV, Worodria WO, Charlebois ED, Srikantiah P, Cattamanchi A, Huber C, Shea YR, Chow Y, Fischer SH. Polymerase chain reaction of secA1 on sputum or oral wash Samples for the diagnosis of pulmonary tuberculosis. Clin Infect Dis. 48: 725-732, 2009.
Fei MW, Sant CA, Kim EJ, Swartzman A, Davis JL, Jarlsberg LG, and Huang L. Severity and outcomes of Pneumocystis pneumonia in patients newly diagnosed with HIV infection: An observational cohort study. Scand J Infect Dis. 1-7, 2009.
Cattamanchi A, Dowdy DW, Davis JL, Worodria W, Yoo S, Joloba M, Matovu J, Hopewell PC, and Huang L. Sensitivity of direct versus concentrated sputum smear microscopy in HIV-infected patients suspected of having pulmonary tuberculosis. BMC Infect Dis. 9: 53, 2009.
Erickson SE, Martin GS, Davis JL, Matthay MA, and Eisner MD. Recent trends in acute lung injury mortality: 1996-2005. Crit Care Med. 37: 1574-9, 2009.
Shea YR, Davis JL, Huang L, Kovacs JA, Masur H, Mulindwa F, Opus S, Chow Y, and Murray PR. High sensitivity and specificity of acid-fast microscopy for diagnosis of pulmonary tuberculosis in an African population with a high prevalence of human immunodeficiency virus. J Clin Microbiol. 47: 1553-5, 2009.
Cattamanchi A, Davis JL, Worodria W, den Boon S, Yoo S, Matovu J, Kiidha J, Nankya F, Kyeyune R, Byanyima P, Andama A, Joloba M, Osmond DH, Hopewell PC, Huang L. Poor specificity of fluorescence microscopy for diagnosing active pulmonary tuberculosis in HIV-infected Ugandans. Int J Tuberc Lung Dis 2009.
