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Dr. Gold received is M.D. degree from Harvard Medical School in
1959. After internal medicine and chief medical residency at the
Beth Israel Hospital in Boston (1959-62), he received his research
training at the Cardiovascular Research Institute, UCSF with Jay
A. Nadel and Julius H. Comroe, Jr., (1962-65) and then joined
the faculty of Harvard Medical School at Children’s Hospital
in 1965 where he set up a new pulmonary laboratory for Dr. Alexander
Nadas to study the pulmonary problems of children with congenital
heart disease. He joined the faculty in the Pulmonary Division
at UCSF in 1969 and became the Director of the Adult Pulmonary
Laboratories, CVRI, UCSF in 1980. His major academic activities
include clinical research programs, training pre and post-doctoral
fellows in all four schools in systems physiology, supervision
of the Adult Pulmonary Laboratories, consulting with industry
on systems physiology, and University service as an officer of
the Faculty Association and Academic Senate.
Study of the function of the respiratory system under resting conditions may provide first clues about the presence of significant respiratory disease. Study of the respiratory system during the stress of exercise, may under cover evidence of such diseases at a much earlier stage. Repeated studies can define the natural history of those diseases and the effects of therapeutic interventions. Current research, as a member of the FAMRI (Flight Attendants Medical Research Institute) Center of Excellence, PI Neal Benowitz) is designed to examine the long-term effects of second hand cigarette smoke on flight attendants. Pilot studies have demonstrated that 40% of nonsmoking flight attendants who worked on commercial airlines prior to the ban on cigarette smoking developed diffusion defects associated with airway obstruction and air trapping. During exercise, all pre-ban flight attendants show an abnormally limited increase in diffusing capacity with increased pulmonary blood flow. Current studies are designed to compare lung function at rest and during exercise in pre-ban fight attendants with post-ban flight attendants, and nonsmokers who live and work at sea level stratified by second-hand smoke exposure.
Pennington DW, Gold WM, Gordon RL, Steiger
D, Ring EJ, Golden JA. Treatment of pulmonary arteriovenous malformations
by therapeutic embolization. Rest and exercise physiology in eight
patients. Am. Rev. Respir. Dis., 145:1047-1051, 1992.
Dean NC; Brown JK; Himelman RB; Doherty JJ; Gold WM; Stulbarg
MS. Oxygen may improve dyspnea and endurance in patients with
chronic obstructive pulmonary disease and only mild hypoxemia.
Am.Rev. Respir. Dis. 146:941-5,1992
Jayr C, Matthay MA, Goldstone J, Gold WM, Wiener-Kronish JP. Preoperative
and intraoperative factors associated with prolonged mechanical
ventilation. A study of patients following major abdominal surgery.
Chest, 103:1231-1236, 1993.
Hellman DB, Kirsch CM, Whiting-O'Keefe Q, Simonson J, Schiller
NB, Petri M, Gamsu G, Gold WM. Dyspnea in ambulatory patients
with SLE: prevalence, severity, and correlation with incremental
exercise testing. J Rheumatol, 22:455-61, 1995.
Eisner MD, Gordon RL, Webb WR, Gold WM, Hilal SE, Edinburgh K,
Golden JA. Pulmonary function improves after expandable metal
stent placement for benign airway obstruction. Chest,15:006-11,
1999.
Hardie GE, Janson S, Boushey HA, Carrieri-Kohlman V, Gold WM. Ethnic Differences: word descriptors used byAfrican American and white asthma patients during induced bronchoconstiction. Chest, 117: 935-943, 2000
SC Johnston, V Singh, HJ Ralston, WM Gold, "Chronic dyspnea and hyperventilation in an awake patient with small subcortical infarcts," Neurology, 57: 2131-3, 2001.
Stulbarg MS, Carrieri-Kohlman V, Demir-Deviren S, Nguten HQ, Adams L, Tsang AH, Duda J, Gold WM, Paul S: Exercise training improves outcomes of a dyspnea self-management program J Cardiopul Rehab, 22: 109-121, 2002.
Hardie GE, Gold WM, Janson S, Carrieir-Kohlman V, Boushey HA. Understanding how asthmatics perceive symptom distress during a methacholine challenge. J Asthma 39: 611-8, 2002.
Janson SL, Fahy JV, Covington JK, Paul SM, Gold WM, Boushey HA. Effects of individual self-management education on clinical, biological, and adherence outcomes in asthma. Am J Med 115:620-6, 2003.
Gold WM, Pulmonary function testing. In: Gold WM ed. Atlas of Procedures in Respiratory Medicine: a companion to the Textbook of Respiratory Medicine, 2002
Gold WM. Pulmonary function testing. In: Mason RJ, Broaddus VC, Murray JF, Nadel JA, eds. Murray and Nadel’s Textbook of Respiratory Medicine, Philadelphia. Elsevier Saunders, 4th edn. Vol 1, 2005.
Gold WM. Clinical exercise testing. In: Mason RJ, Broaddus VC, Murray JF, Nadel JA, eds. Murray and Nadel’s Textbook of Respiratory Medicine, Philadelphia. Elsevier Saunders, 4th edn. Vol 1, 2005
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