Dr Hopewell received his M.D. degree from West Virginia University in 1965 and trained in internal medicine and pulmonary disease at the University of California, San Francisco. He joined the faculty at UCSF in 1973 and has remained there since. His other experience includes two years in the U.S. Public Health Service, one year with the Ministry of Health and the World Health Organization in Peru, one year with the Stop TB department at WHO, Geneva, and six months with the Government of Nigeria, all working in tuberculosis control.
Research Interests
Dr. Hopewell is Professor of Medicine and Principal Investigator for the Curry International Tuberculosis Center, which he founded 17 years ago. He has been actively involved in clinical and epidemiological research on tuberculosis and pulmonary complications of HIV infection for the past 37 years and has had continuous NIH support for the past 30 years. Currently he is PI for 2 RO1 awards from NIAID examining the relationship of the genotype of Mycobacterium tuberculosis to the pathogenicity of the organism. In addition he is PI for a UO1 award (International Collaborations in Infectious Disease Research), also from NIAID, examining transmission of M. tuberculosis and M. bovis in rural Tanzania. Core funding for the Curry Center as a Regional Training and Medical Consultation Center is from a CDC grant for which Dr. Hopewell s the PI. At the Curry Center Dr Hopewell leads an active program for technical assistance to international tuberculosis control programs via funding from USAID, WHO and other organizations. Dr Hopewell has a long record of successful mentorship with approximately 90% of his trainees either in academic positions or in positions of influence in organizations such as the Bill and Melinda Gates Foundation and WHO. In recognition of his record of mentorship, in 2008 Dr. Hopewell was awarded the UCSF award for lifetime mentoring. Dr. Hopewell continues to be actively involved in the clinical activities of the Division, attending both in the Medical ICU and on the Pulmonary Consultation Service.
Recent Publications
Cattamanchi A, Dantes RB, Metcalfe JZ, Jarlsberg LG, Grinsdale J, Kawamura LM, Osmond D, Hopewell PC, Nahid P. Clinical characteristics and treatment outcomes of patients with isoniazid-monoresistant tuberculosis. Clin Infect Dis. 48: 2009;179-85
Metcalfe JZ, Cattamanchi A, Vittinghoff E, Ho C, Grinsdale J, Hopewell PC, Kawamura LM, Nahid P. Evaluation of Quantitative Interferon-{gamma} Response for Risk Stratification of Active Tuberculosis Suspects Am J Respir Crit Care Med. 2009 Oct 1. [Epub ahead of print
