Dr. Huang graduated from Johns Hopkins University in 1985 (B.A., Biology) and received his M.D. degree from Columbia University, College of Physicians and Surgeons in 1989. He completed a categorical Internal Medicine residency at Columbia Presbyterian Medical Center in New York (1992) and his Pulmonary and Critical Care Medicine fellowship at University of California, San Francisco (1995). Dr. Huang joined the faculty at University of California, San Francisco in 1995, where he is an attending physician in the Department of Medicine at San Francisco General Hospital with dual appointments in the Division of Pulmonary and Critical Care Medicine and the HIV/AIDS Division. Currently, he is the Chief of the San Francisco General Hospital AIDS Chest Clinic.
Dr. Huang's main clinical and clinical research interests are in HIV-associated pulmonary diseases, including Pneumocystis pneumonia (PCP), tuberculosis (TB), bacterial pneumonia, HIV-associated chronic obstructive lung diseases, and HIV-associated pulmonary arterial hypertension. He has clinical and translational research collaborations with co investigators at the National Institutes of Health, the University of Cincinnati, the University of North Carolina, the University of Pittsburgh, Yale University, the University of Colorado, University College, London, United Kingdom, and Makerere University Kampala, Uganda as well as colleagues at San Francisco General Hospital and University of California, San Francisco. In addition, Dr. Huang has independent studies on PCP and ICU outcomes among HIV-infected patients at San Francisco General Hospital. These collaborative studies are supported through an NIH K24 Midcareer Investigator Award in Patient-Oriented Research Award and 5 NIH R01 Awards. Current research studies include: (1) An International (San Francisco, London, Kampala) cohort study of HIV-associated opportunistic pneumonias; (2) Development and validation of several new molecular applications to study PCP epidemiology, diagnosis, drug-resistance, and host immune response; (3) Development and validation of several new molecular applications to study TB and bacterial pneumonia epidemiology and diagnosis; (4) Comprehensive molecular-epidemiology study that addresses whether PCP results from person-to-person transmission (as has been convincingly demonstrated from animal-to-animal laboratory studies) and whether disease results from reactivation of latent infection or from recent exposure and infection.
For more details about the International HIV-associated Opportunistic Pneumonias (IHOP) Study, please see the website of the Makerere University – UCSF Research Collaboration: http://www.muucsf.org/Biog/laurence.asp
Morris, A, Masur, H, and Huang, L. Current issues in critical care of the human immunodeficiency virus-infected patient. Crit Care Med2006;34(1):42-49.
Huang, L, Quartin, A, Jones, D, and Havlir, DV. Intensive care of patients with HIV infection. N Engl J Med2006;355(2):173-181.
*Huang, L, *Daly, KR, *Morris, A, Koch, J, Crothers, K, Levin, L, Eiser, S, Satwah, S, Zucchi, P, and Walzer, PD. Antibody response to Pneumocystis jirovecii major surface glycoprotein. Emerg Infect Dis2006;12(8):1231-1237 *co-first authors.
Huang, L, Morris, A, Limper, AH, and Beck, JM. An Official ATS Workshop Summary: Recent Advances and Future Directions in Pneumocystis Pneumonia (PCP). Proc Am Thorac Soc2006;3(8):655-664.
de Oliveira, A, Unnasch, TR, Crothers, K, Eiser, S, Zucchi, P, Moir, J, Beard, CB, Lawrence, GG, and Huang, L. Performance of a molecular viability assay for the diagnosis of Pneumocystis pneumonia in HIV-infected patients. Diagn Microbiol Infect Dis 2007;57:169-176.
Huang, L. Pulmonary Manifestations of Human Immunodeficiency Virus Infection and Acquired Immunodeficiency Syndrome. In Goldman, L and Ausiello, D, eds. Cecil Medicine. 23rd edition. Philadelphia: Saunders Elsevier, 2007. pp. 2585-2597.
Davis, JL and Huang, L. Pneumocystis Pneumonia. In Volberding, PA, Sande, MA, Lange, J, and Greene, WC, eds. Global HIV/AIDS Medicine. First edition. Philadelphia: Elsevier, Inc., 2007. In Press.
Huang, L. Respiratory Disease. In Dolin, R, Masur, H, and Saag, M, eds. AIDS Therapy. Third edition. New York, Churchill Livingstone, 2007. In Press.
Huang, L and Masur, H. Pneumocystis. In Dolin, R, Masur, H, and Saag, MS, eds. AIDS Therapy. Third edition. New York, Churchill Livingstone, 2007. In Press.
Morris, AM, Crothers, K, and Huang, L. Human Immunodeficiency Virus in the Intensive Care Unit. In Civetta, Taylor, Kirby: Critical Care Medicine, 4th Edition. Lippincott Williams and Wilkins, 2008. In Press.
Morris, A, Wei, K, Afshar, K, and Huang, L. Epidemiology and clinical significance of Pneumocystis colonization. Journal of Infectious Diseases 2007. In Press. |
