John M. Luce, M.D.
Professor of Clinical Medicine and Anesthesia

University of California San Francisco
San Francisco General Hospital
Box 0841, Bldg 4F4 3c-38
San Francisco, California 94143
phone: (415) 206-8289
fax: (415) 695-1551
email: john.luce@sfdph.org

Dr. Luce attended Cate School in Carpinteria, CA from 1956-1959 and Stanford University from 1959-1963. He worked as a political press secretary and magazine writer and editor from 1963-1970. He attended the School of Medicine of the University of California, San Francisco from 1970-1974. He was a resident and a fellow in Internal Medicine at the University of Colorado, Denver from 1974-1978 and a fellow in Respiratory Diseases at the University of Washington, Seattle, from 1978-1981. He joined the faculty at the University of California, San Francisco in 1981 and has been based at San Francisco General Hospital since that time. From 1993-1994 he was a Pew fellow in Health Policy at the University of California, San Francisco.

Dr. Luce is currently Associate Director of the Medical-Surgical Intensive Care Unit and Medical Director of Quality, Utilization, and Risk Management at San Francisco General Hospital.

Research Interests

Dr. Luce conducts clinical research in the areas of 1) quality improvement and health policy, 2) biomedical ethics and end-of-life care, and 3) acute lung injury and the acute respiratory distress syndrome.

Recent Publications:

Quality improvement and health policy

1) Luce JM, Rubenfeld GD. Can health care costs be reduced by limiting care at the end of life? Am J Respir Crit Care Med 2002;165:750-754.

2) Clarke EB, Curtis JR, Luce JM, Levy M, Danis M, Nelson J, Solomon MZ for the Robert Wood Johnson Foundation Critical Care End-of-Life Peer Workshop Members. Quality indicators for end-of-life care in the intensive care unit. Crit Care Med 2003;31:2255-2262.

Biomedical ethics and end-of-life care

1) Luce JM, Cook DJ, Martin TR, Angus D, Boushey HA, Curtis JR, Heffner JE, Lanken PN, Levy MM, Polite PY, Rocker GM, Truog RD. The ethical conduct of clinical research involving critically ill patients in the United States and Canada: principles and recommendations. Am J Respir Crit Care Med 2004;170:1375-1384.

2) Silverman HJ, Luce JM, Lanken PN, Morris AH, Harabin AL, Oldmixon CF, Thompson BT, Bernard GR for the NHLBI Acute Respiratory Distress Syndrome Clinical Trials Network (ARDSNet). Recommendations for informed consent forms for critical care clinical trials. Crit Care Med 2005;33:867-882.

Acute lung injury and the acute respiratory distress syndrome

1) Hough CL, Kallet RH, Ranieri VM, Rubenfeld GD, Luce JM, Hudson LD. Intrinsic positive end-expiratory pressure in Acute Respiratory Distress Syndrome (ARDS) network subjects. Crit Care Med 2005;33:527-532.

2) Kallet RH, Jasmer RM, Pitter J-F, Tang JF, Campbell AR, Dicker R, Hemphill C, Luce JM. Clinical implementation of the ARDS network protocol is associated with reduced hospital mortality compared with historical controls. Crit Care Med 2005;33:925-929.