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Research
Clinical trials are formal, controlled protocols designed to test the effectiveness of new treatments, including novel drugs, types of intervention, or combinations of therapy. To view more detailed information please select the Research Center or Clinical Trial below:  
Major research activities of the Division can also be accessed through the Biosketches of individual faculty.
AIDS-related Pulmonary Disease Studies - San Francisco General Hospital is participating in several clinical and translational research studies involving HIV-infected patients with Pneumocystis Pneumonia (PCP) and other HIV-associated opportunistic pneumonias, HIV-infected patients with COPD, HIV-infected patients with pulmonary arterial hypertension, studies examining the lung microbiome in persons with HIV infection, and studies with the NHLBI-funded Lung HIV Study and the NHLBI-funded Lung HIV Microbiome Project.
Lung Biology Center - The mission of the Lung Biology Center (LBC) is to use cell and molecular biology to study important questions about diseases of the lung and airways. The Lung Biology Center is a division of the Department of Medicine at the University of California San Francisco (UCSF), and is based at the San Francisco General Hospital Medical Center campus.
Acute Respiratory Distress Syndrome - UCSF is a major center for the clinical care of critically ill patients with ARDS (also know as Acute Lung Injury) at all the affiliated hospitals, including NIH supported basic and clinical interdisciplinary research on ARDS, UCSF also is an NIH supported center for carrying out phase II and phase III clinical trials.  Several faculty members in the Departments of Medicine, Anesthesia, Surgery, and Pediatrics as well as post-doctoral fellows are focused on basic research and clinical research issues in ARDS, and related critical care issues, in both adults and children.
Asthma Clinical Research Center - The UCSF Asthma Research Center needs participants for asthma research studies. Studies are sponsored by the National Institutes of Health and pharmaceutical companies
Genetic Epidemoiology of Asthma & Drug Response - We have assembled the largest pediatric asthma genetic study of minority children in the U.S. We have recruited and phenotyped over 6,000 Latino and African American children from throughout the U.S. We have detailed phenotype information including spirometry, bronchodilator response, total IgE, skin prick testing, genome-wide data, detailed information on socioeconomic status (SES) and geocoded air pollution on most study participants. More detail can be found at (http://bts.ucsf.edu/burchard/team_members.php).
We are also part of the National Asthma Genetics Consortium, EVE.
Tuberculosis Research at San Francisco General Hospital - There is a wide variety of clinical- and laboratory-based research on tuberculosis by investigators based at San Francisco General Hospital. Active research includes domestic projects through the San Francisco Tuberculosis Clinic and the TB Epidemiology Studies Consortium (TBESC) and international projects through collaborations in Tanzania, Vietnam, Uganda, and Zimbabwe. In addition, investigators are involved with TB-related technical assistance in the Western Region of the United States and internationally through the Francis J. Curry International Tuberculosis Center.
UCSF Interstitial Lung Disease Program - Our investigators pursue a broad spectrum of research from clarification of molecular pathways of lung inflammation and fibrosis to clinical research into potential novel therapies.
Respiratory Epidemiology Group - We are an interdisciplinary group of investigators who study the epidemiology and health outcomes of pulmonary diseases. Our mission is to apply state-of-the-art epidemiologic and biostatistical methods to study health outcomes in a broad array of pulmonary diseases, to identify risk factors for adverse health outcomes among persons with chronic pulmonary diseases, and to translate science into policy aimed at reducing the global burden of respiratory disease
Human Exposure Laboratory - The Human Exposure Laboratory (HEL), based at the San Francisco General Hospital Medical Center campus, is one of a small number of facilities in the U.S. that are equipped to conduct controlled human exposure studies of inhaled pollutants.  The HEL's mission is to study the health effects of air pollutants with emphasis on toxicology and oxidative stress as mechanisms by which inhaled pollutants contribute to cardiopulmonary pathophysiology in health and disease. 
SF VAMC Pulmonary Research Group - The VA Pulmonary Research Group focuses on basic and translational researching into responses of airway and alveolar cells to inflammation and injury, emphasizing molecular and cellular mechanisms of remodeling, fluid transport, and antibacterial defense via studies of key proteins, including proteases, ion channels, and components of epithelial tight junctions and extracellular matrix.  The Pulmonary Research Group also supports related clinical and human genetic research into diseases such asthma, COPD, sepsis, lung cancer, and sleep apnea.

 

     
Updated: 2/13/09
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