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Faculty Profiles

John Balmes, MD
M_MED-OCCM-ZSFG
Professor

1001 Potrero Ave
San Francisco, CA 94110
415-206-8314
john.balmes@ucsf.edu

Dr. Balmes received his MD degree from Mount Sinai School of Medicine in 1976. After internal medicine training at Mount Sinai and pulmonary subspecialty, occupational medicine, and research training at Yale, he joined the faculty of USC in 1982. He joined the faculty at UCSF in 1986 and is currently Professor and Division Chief of Occupational and Environmental Medicine at San Francisco General Hospital (SFGH). His major academic activities include his research laboratory, several collaborative epidemiological research projects, various advisory and editorial committees, and direction of the clinical occupational/environmental medicine division at SFGH.


Dr. Balmes' laboratory, the Human Exposure Laboratory (HEL), has been studying the respiratory health effects of various air pollutants for the past 27 years. Recently, the HEL has been focusing on the airway inflammatory effects of ozone, secondhand tobacco smoke, and wood smoke. The HEL was the first group to demonstrate a) histological evidence of ozone-induced airway injury and inflammation in human subjects, b) that asthmatic subjects have greater inflammatory responses to ozone than normal subjects, c) that ozone-induced inflammatory responses in normal subjects attenuate with short-term exposures on consecutive days in the lung, and d) that asthmatic subjects recruit macrophages to the airways with consecutive day exposures. The lab is currently studying the impact of a genetic polymorphism of the antioxidant enzyme, Glutathione-S-transferase M1, on the susceptibility of asthmatic subjects to ozone. We are also studying the relationship of acute airway inflammatory responses to acute cardiovascular responses after both ozone and secondhand tobacco smoke.


Dr. Balmes is also collaborating on several epidemiological projects that are run out of the UC Berkeley School of Public Health where he is a Professor of Environmental Health Sciences. One such project is called the Children's Health and Air Pollution Study (CHAPS). The overall specific goal of CHAPS is to assess the impact of air pollution on the health of children living in the San Joaquin Valley, including adverse effects on immune function that may increase the risk of asthma onset and exacerbation. A second project involves study of the effects of biomass smoke exposure on chronic respiratory health of children and adult women in rural Guatemala. A third line of research involves the effects of arsenic in drinking water on lung health in both Bangladesh and Chile. Yet another project involves the effect of chronic exposure to hydrogen sulfide on lung function in Rotorua, NZ.

Featured Videos

Recent Articles (255)

Nardone A, Ferreccio C, Acevedo J, Enanoria W, Blair A, Smith AH, Balmes J, Steinmaus C. The impact of BMI on non-malignant respiratory symptoms and lung function in arsenic exposed adults of Northern Chile. Environ Res. 2017 Oct; 158:710-719.

Blount RJ, Daly KR, Fong S, Chang E, Grieco K, Greene M, Stone S, Balmes J, Miller RF, Walzer PD, Huang L. Effects of clinical and environmental factors on bronchoalveolar antibody responses to Pneumocystis jirovecii: A prospective cohort study of HIV+ patients. PLoS One. 2017; 12(7):e0180212.

Johannson KA, Vittinghoff E, Morisset J, Lee JS, Balmes JR, Collard HR. Home monitoring improves endpoint efficiency in idiopathic pulmonary fibrosis. Eur Respir J. 2017 Jul; 50(1).

Thurston G, Balmes J. We Need to "Think Different" about Particulate Matter. Am J Respir Crit Care Med. 2017 Jul 01; 196(1):6-7.

Sigsgaard T, Balmes J. Environmental Effects of Intensive Livestock Farming. Am J Respir Crit Care Med. 2017 Jun 19.

Carty P, Cooper MR, Barr A, Neitzel RL, Balmes J, Rempel D. The Effects of Bit Wear on Respirable Silica Dust, Noise and Productivity: A Hammer Drill Bench Study. Ann Work Expo Health. 2017 Jun 08.

Navarro KM, Cisneros R, Noth EM, Balmes JR, Hammond SK. Occupational Exposure to Polycyclic Aromatic Hydrocarbon of Wildland Firefighters at Prescribed and Wildland Fires. Environ Sci Technol. 2017 Jun 06; 51(11):6461-6469.

Lee EY, Lin J, Noth EM, Hammond SK, Nadeau KC, Eisen EA, Balmes JR. Traffic-Related Air Pollution and Telomere Length in Children and Adolescents Living in Fresno, CA: A Pilot Study. J Occup Environ Med. 2017 May; 59(5):446-452.

Padula AM, Yang W, Carmichael SL, Lurmann F, Balmes J, Hammond SK, Shaw GM. Air pollution, neighborhood acculturation factors, and neural tube defects among Hispanic women in California. Birth Defects Res. 2017 Apr 03; 109(6):403-422.

Thurston GD, Kipen H, Annesi-Maesano I, Balmes J, Brook RD, Cromar K, De Matteis S, Forastiere F, Forsberg B, Frampton MW, Grigg J, Heederik D, Kelly FJ, Kuenzli N, Laumbach R, Peters A, Rajagopalan ST, Rich D, Ritz B, Samet JM, Sandstrom T, Sigsgaard T, Sunyer J, Brunekreef B. A joint ERS/ATS policy statement: what constitutes an adverse health effect of air pollution? An analytical framework. Eur Respir J. 2017 Jan; 49(1).

Mortimer K, Ndamala CB, Naunje AW, Malava J, Katundu C, Weston W, Havens D, Pope D, Bruce NG, Nyirenda M, Wang D, Crampin A, Grigg J, Balmes J, Gordon SB. A cleaner burning biomass-fuelled cookstove intervention to prevent pneumonia in children under 5 years old in rural Malawi (the Cooking and Pneumonia Study): a cluster randomised controlled trial. Lancet. 2016 Dec 06.

Antony VB, Redlich CA, Pinkerton KE, Balmes J, Harkema JR. National Institute of Environmental Health Sciences: 50 Years of Advancing Science and Improving Lung Health. Am J Respir Crit Care Med. 2016 Nov 15; 194(10):1190-1195.

Navarro KM, Cisneros R, O'Neill SM, Schweizer D, Larkin NK, Balmes JR. Air-Quality Impacts and Intake Fraction of PM2.5 during the 2013 Rim Megafire. Environ Sci Technol. 2016 Nov 1; 50(21):11965-11973.

Sarfaty M, Kreslake J, Ewart G, Guidotti TL, Thurston GD, Balmes JR, Maibach EW. Survey of International Members of the American Thoracic Society on Climate Change and Health. Ann Am Thorac Soc. 2016 Oct; 13(10):1808-1813.

Bayram H, Bauer AK, Abdalati W, Carlsten C, Pinkerton KE, Thurston GD, Balmes JR, Takaro TK. Environment, Global Climate Change, and Cardiopulmonary Health. Am J Respir Crit Care Med. 2016 Sep 21.

Smith KR, Woodward A, Lemke B, Otto M, Chang CJ, Mance AA, Balmes J, Kjellstrom T. The last Summer Olympics? Climate change, health, and work outdoors. Lancet. 2016 Aug 13; 388(10045):642-4.

Reid CE, Jerrett M, Tager IB, Petersen ML, Mann JK, Balmes JR. Differential respiratory health effects from the 2008 northern California wildfires: A spatiotemporal approach. Environ Res. 2016 Oct; 150:227-35.

Nishimura KK, Iwanaga K, Oh SS, Pino-Yanes M, Eng C, Keswani A, Roth LA, Nguyen EA, Thyne SM, Farber HJ, Serebrisky D, Meade K, LeNoir MA, Rodriguez-Cintron W, Borrell LN, Bibbins-Domingo K, Lurmann F, Sen S, Rodriguez-Santana JR, Brigino-Buenaventura E, Avila PC, Balmes JR, Kumar R, Burchard EG. Early-life ozone exposure associated with asthma without sensitization in Latino children. J Allergy Clin Immunol. 2016 Jun 11.

Neophytou AM, White MJ, Oh SS, Thakur N, Galanter JM, Nishimura KK, Pino-Yanes M, Torgerson DG, Gignoux CR, Eng C, Nguyen EA, Hu D, Mak AC, Kumar R, Seibold MA, Davis A, Farber HJ, Meade K, Avila PC, Serebrisky D, Lenoir MA, Brigino-Buenaventura E, Rodriguez-Cintron W, Bibbins-Domingo K, Thyne SM, Williams LK, Sen S, Gilliland FD, Gauderman WJ, Rodriguez-Santana JR, Lurmann F, Balmes JR, Eisen EA, Burchard EG. Air Pollution and Lung Function in Minority Youth with Asthma in the GALA II (Genes-Environments and Admixture in Latino Americans) and SAGE II (Study of African Americans, Asthma, Genes, and Environments) Studies. Am J Respir Crit Care Med. 2016 Jun 1; 193(11):1271-80.

Ware LB, Zhao Z, Koyama T, May AK, Matthay MA, Lurmann FW, Balmes JR, Calfee CS. Long-Term Ozone Exposure Increases the Risk of Developing the Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2016 May 15; 193(10):1143-50.

Reid CE, Brauer M, Johnston FH, Jerrett M, Balmes JR, Elliott CT. Critical Review of Health Impacts of Wildfire Smoke Exposure. Environ Health Perspect. 2016 Sep; 124(9):1334-43.

Heinzerling AP, Guarnieri MJ, Mann JK, Diaz JV, Thompson LM, Diaz A, Bruce NG, Smith KR, Balmes JR. Lung function in woodsmoke-exposed Guatemalan children following a chimney stove intervention. Thorax. 2016 May; 71(5):421-8.

Pope D, Diaz E, Smith-Sivertsen T, Lie RT, Bakke P, Balmes JR, Smith KR, Bruce NG. Erratum: "Exposure to Household Air Pollution from Wood Combustion and Association with Respiratory Symptoms and Lung Function in Nonsmoking Women: Results from the RESPIRE Trial, Guatemala". Environ Health Perspect. 2016 Mar; 124(3):A48.

Raanan R, Balmes JR, Harley KG, Gunier RB, Magzamen S, Bradman A, Eskenazi B. Decreased lung function in 7-year-old children with early-life organophosphate exposure. Thorax. 2016 Feb; 71(2):148-53.

Balmes JR. Exposure to Endotoxin in Household Dust. To Wheeze or Not to Wheeze. Am J Respir Crit Care Med. 2015 Dec 1; 192(11):1265-6.

Guarnieri M, Diaz E, Pope D, Eisen EA, Mann J, Smith KR, Smith-Sivertsen T, Bruce NG, Balmes JR. Lung Function in Rural Guatemalan Women Before and After a Chimney Stove Intervention to Reduce Wood Smoke Exposure: Results From the Randomized Exposure Study of Pollution Indoors and Respiratory Effects and Chronic Respiratory Effects of Early Childhood Exposure to Respirable Particulate Matter Study. Chest. 2015 Nov 1; 148(5):1184-92.

Leroy P, Tham A, Wong H, Tenney R, Chen C, Stiner R, Balmes JR, Paquet AC, Arjomandi M. Inflammatory and repair pathways induced in human bronchoalveolar lavage cells with ozone inhalation. PLoS One. 2015; 10(6):e0127283.

Assad NA, Balmes J, Mehta S, Cheema U, Sood A. Chronic obstructive pulmonary disease secondary to household air pollution. Semin Respir Crit Care Med. 2015 Jun; 36(3):408-21.

Arjomandi M, Wong H, Donde A, Frelinger J, Dalton S, Ching W, Power K, Balmes JR. Exposure to medium and high ambient levels of ozone causes adverse systemic inflammatory and cardiac autonomic effects. Am J Physiol Heart Circ Physiol. 2015 Jun 15; 308(12):H1499-509.

Bates MN, Crane J, Balmes JR, Garrett N. Investigation of hydrogen sulfide exposure and lung function, asthma and chronic obstructive pulmonary disease in a geothermal area of New Zealand. PLoS One. 2015; 10(3):e0122062.

Reid CE, Jerrett M, Petersen ML, Pfister GG, Morefield PE, Tager IB, Raffuse SM, Balmes JR. Spatiotemporal prediction of fine particulate matter during the 2008 northern California wildfires using machine learning. Environ Sci Technol. 2015 Mar 17; 49(6):3887-96.

Sarfaty M, Bloodhart B, Ewart G, Thurston GD, Balmes JR, Guidotti TL, Maibach EW. American Thoracic Society member survey on climate change and health. Ann Am Thorac Soc. 2015 Feb; 12(2):274-8.

Smith KR, Balmes JR, Guarnieri MJ. Cardiovascular risk and events and country income stratum. N Engl J Med. 2015 Jan 15; 372(3):289.

Hew KM, Walker AI, Kohli A, Garcia M, Syed A, McDonald-Hyman C, Noth EM, Mann JK, Pratt B, Balmes J, Hammond SK, Eisen EA, Nadeau KC. Childhood exposure to ambient polycyclic aromatic hydrocarbons is linked to epigenetic modifications and impaired systemic immunity in T cells. Clin Exp Allergy. 2015 Jan; 45(1):238-48.

Holland N, Davé V, Venkat S, Wong H, Donde A, Balmes JR, Arjomandi M. Ozone inhalation leads to a dose-dependent increase of cytogenetic damage in human lymphocytes. Environ Mol Mutagen. 2015 May; 56(4):378-87.

Balmes JR, Abraham JL, Dweik RA, Fireman E, Fontenot AP, Maier LA, Muller-Quernheim J, Ostiguy G, Pepper LD, Saltini C, Schuler CR, Takaro TK, Wambach PF. An official American Thoracic Society statement: diagnosis and management of beryllium sensitivity and chronic beryllium disease. Am J Respir Crit Care Med. 2014 Nov 15; 190(10):e34-59.

Pope D, Diaz E, Smith-Sivertsen T, Lie RT, Bakke P, Balmes JR, Smith KR, Bruce NG. Exposure to household air pollution from wood combustion and association with respiratory symptoms and lung function in nonsmoking women: results from the RESPIRE trial, Guatemala. Environ Health Perspect. 2015 Apr; 123(4):285-92.

Steinmaus C, Ferreccio C, Yuan Y, Acevedo J, González F, Perez L, Cortés S, Balmes JR, Liaw J, Smith AH. Elevated lung cancer in younger adults and low concentrations of arsenic in water. Am J Epidemiol. 2014 Dec 1; 180(11):1082-7.

Raanan R, Harley KG, Balmes JR, Bradman A, Lipsett M, Eskenazi B. Early-life exposure to organophosphate pesticides and pediatric respiratory symptoms in the CHAMACOS cohort. Environ Health Perspect. 2015 Feb; 123(2):179-85.

Thompson LM, Yousefi P, Peñaloza R, Balmes J, Holland N. Genetic modification of the effect of maternal household air pollution exposure on birth weight in Guatemalan newborns. Reprod Toxicol. 2014 Dec; 50:19-26.

Ortega Hinojosa AM, Davies MM, Jarjour S, Burnett RT, Mann JK, Hughes E, Balmes JR, Turner MC, Jerrett M. Developing small-area predictions for smoking and obesity prevalence in the United States for use in Environmental Public Health Tracking. Environ Res. 2014 Oct; 134:435-52.

Gordon SB, Bruce NG, Grigg J, Hibberd PL, Kurmi OP, Lam KB, Mortimer K, Asante KP, Balakrishnan K, Balmes J, Bar-Zeev N, Bates MN, Breysse PN, Buist S, Chen Z, Havens D, Jack D, Jindal S, Kan H, Mehta S, Moschovis P, Naeher L, Patel A, Perez-Padilla R, Pope D, Rylance J, Semple S, Martin WJ. Respiratory risks from household air pollution in low and middle income countries. Lancet Respir Med. 2014 Oct; 2(10):823-60.

Rice MB, Thurston GD, Balmes JR, Pinkerton KE. Reply: the largest problem with climate change policy is not a future event. Am J Respir Crit Care Med. 2014 Jul 1; 190(1):117.

Padula AM, Balmes JR, Eisen EA, Mann J, Noth EM, Lurmann FW, Pratt B, Tager IB, Nadeau K, Hammond SK. Ambient polycyclic aromatic hydrocarbons and pulmonary function in children. J Expo Sci Environ Epidemiol. 2015 May; 25(3):295-302.

Humblet O, Diaz-Ramirez LG, Balmes JR, Pinney SM, Hiatt RA. Perfluoroalkyl chemicals and asthma among children 12-19 years of age: NHANES (1999-2008). Environ Health Perspect. 2014 Oct; 122(10):1129-33.

Guarnieri M, Balmes JR. Outdoor air pollution and asthma. Lancet. 2014 May 3; 383(9928):1581-92.

Picciotto S, Chevrier J, Balmes J, Eisen EA. Hypothetical interventions to limit metalworking fluid exposures and their effects on COPD mortality: G-estimation within a public health framework. Epidemiology. 2014 May; 25(3):436-43.

Guarnieri MJ, Diaz JV, Basu C, Diaz A, Pope D, Smith KR, Smith-Sivertsen T, Bruce N, Solomon C, McCracken J, Balmes JR. Effects of woodsmoke exposure on airway inflammation in rural Guatemalan women. PLoS One. 2014; 9(3):e88455.

Rice MB, Thurston GD, Balmes JR, Pinkerton KE. Climate change. A global threat to cardiopulmonary health. Am J Respir Crit Care Med. 2014 Mar 1; 189(5):512-9.

Burnett RT, Pope CA, Ezzati M, Olives C, Lim SS, Mehta S, Shin HH, Singh G, Hubbell B, Brauer M, Anderson HR, Smith KR, Balmes JR, Bruce NG, Kan H, Laden F, Prüss-Ustün A, Turner MC, Gapstur SM, Diver WR, Cohen A. An integrated risk function for estimating the global burden of disease attributable to ambient fine particulate matter exposure. Environ Health Perspect. 2014 Apr; 122(4):397-403.

Balmes JR, Cisternas M, Quinlan PJ, Trupin L, Lurmann FW, Katz PP, Blanc PD. Annual average ambient particulate matter exposure estimates, measured home particulate matter, and hair nicotine are associated with respiratory outcomes in adults with asthma. Environ Res. 2014 Feb; 129:1-10.

Smith KR, Bruce N, Balakrishnan K, Adair-Rohani H, Balmes J, Chafe Z, Dherani M, Hosgood HD, Mehta S, Pope D, Rehfuess E. Millions dead: how do we know and what does it mean? Methods used in the comparative risk assessment of household air pollution. Annu Rev Public Health. 2014; 35:185-206.

Blount RJ, Djawe K, Daly KR, Jarlsberg LG, Fong S, Balmes J, Miller RF, Walzer PD, Huang L. Ambient air pollution associated with suppressed serologic responses to Pneumocystis jirovecii in a prospective cohort of HIV-infected patients with Pneumocystis pneumonia. PLoS One. 2013; 8(11):e80795.

Johannson KA, Vittinghoff E, Lee K, Balmes JR, Ji W, Kaplan GG, Kim DS, Collard HR. Acute exacerbation of idiopathic pulmonary fibrosis associated with air pollution exposure. Eur Respir J. 2014 Apr; 43(4):1124-31.

Pantell M, Rehkopf D, Jutte D, Syme SL, Balmes J, Adler N. Social isolation: a predictor of mortality comparable to traditional clinical risk factors. Am J Public Health. 2013 Nov; 103(11):2056-62.

Dauphiné DC, Smith AH, Yuan Y, Balmes JR, Bates MN, Steinmaus C. Case-control study of arsenic in drinking water and lung cancer in California and Nevada. Int J Environ Res Public Health. 2013 Aug; 10(8):3310-24.

Nishimura KK, Galanter JM, Roth LA, Oh SS, Thakur N, Nguyen EA, Thyne S, Farber HJ, Serebrisky D, Kumar R, Brigino-Buenaventura E, Davis A, LeNoir MA, Meade K, Rodriguez-Cintron W, Avila PC, Borrell LN, Bibbins-Domingo K, Rodriguez-Santana JR, Sen S, Lurmann F, Balmes JR, Burchard EG. Early-life air pollution and asthma risk in minority children. The GALA II and SAGE II studies. Am J Respir Crit Care Med. 2013 Aug 1; 188(3):309-18.

Takaro TK, Knowlton K, Balmes JR. Climate change and respiratory health: current evidence and knowledge gaps. Expert Rev Respir Med. 2013 Aug; 7(4):349-61.

Smith AH, Yunus M, Khan AF, Ercumen A, Yuan Y, Smith MH, Liaw J, Balmes J, von Ehrenstein O, Raqib R, Kalman D, Alam DS, Streatfield PK, Steinmaus C. Chronic respiratory symptoms in children following in utero and early life exposure to arsenic in drinking water in Bangladesh. Int J Epidemiol. 2013 Aug; 42(4):1077-86.

Balmes JR. Asbestos and lung cancer: what we know. Am J Respir Crit Care Med. 2013 Jul 1; 188(1):8-9.

Schick SF, Farraro KF, Perrino C, Sleiman M, van de Vossenberg G, Trinh MP, Hammond SK, Jenkins BM, Balmes J. Thirdhand cigarette smoke in an experimental chamber: evidence of surface deposition of nicotine, nitrosamines and polycyclic aromatic hydrocarbons and de novo formation of NNK. Tob Control. 2014 Mar; 23(2):152-9.

Bates MN, Garrett N, Crane J, Balmes JR. Associations of ambient hydrogen sulfide exposure with self-reported asthma and asthma symptoms. Environ Res. 2013 Apr; 122:81-7.

Rylance J, Gordon SB, Naeher LP, Patel A, Balmes JR, Adetona O, Rogalsky DK, Martin WJ. Household air pollution: a call for studies into biomarkers of exposure and predictors of respiratory disease. Am J Physiol Lung Cell Mol Physiol. 2013 May 1; 304(9):L571-8.

Blanc PD, Quinlan PJ, Katz PP, Balmes JR, Trupin L, Cisternas MG, Wymer L, Vesper SJ. Higher environmental relative moldiness index values measured in homes of adults with asthma, rhinitis, or both conditions. Environ Res. 2013 Apr; 122:98-101.

Jarjour S, Jerrett M, Westerdahl D, de Nazelle A, Hanning C, Daly L, Lipsitt J, Balmes J. Cyclist route choice, traffic-related air pollution, and lung function: a scripted exposure study. Environ Health. 2013; 12:14.

Steinmaus CM, Ferreccio C, Romo JA, Yuan Y, Cortes S, Marshall G, Moore LE, Balmes JR, Liaw J, Golden T, Smith AH. Drinking water arsenic in northern chile: high cancer risks 40 years after exposure cessation. Cancer Epidemiol Biomarkers Prev. 2013 Apr; 22(4):623-30.

Schick SF, van den Vossenberg G, Luo A, Whitlatch A, Jacob P, Balmes J, Shusterman D. Thirty minute-exposure to aged cigarette smoke increases nasal congestion in nonsmokers. J Toxicol Environ Health A. 2013; 76(10):601-13.

Lim SS, Vos T, Flaxman AD, Danaei G, Shibuya K, Adair-Rohani H, Amann M, Anderson HR, Andrews KG, Aryee M, Atkinson C, Bacchus LJ, Bahalim AN, Balakrishnan K, Balmes J, Barker-Collo S, Baxter A, Bell ML, Blore JD, Blyth F, Bonner C, Borges G, Bourne R, Boussinesq M, Brauer M, Brooks P, Bruce NG, Brunekreef B, Bryan-Hancock C, Bucello C, Buchbinder R, Bull F, Burnett RT, Byers TE, Calabria B, Carapetis J, Carnahan E, Chafe Z, Charlson F, Chen H, Chen JS, Cheng AT, Child JC, Cohen A, Colson KE, Cowie BC, Darby S, Darling S, Davis A, Degenhardt L, Dentener F, Des Jarlais DC, Devries K, Dherani M, Ding EL, Dorsey ER, Driscoll T, Edmond K, Ali SE, Engell RE, Erwin PJ, Fahimi S, Falder G, Farzadfar F, Ferrari A, Finucane MM, Flaxman S, Fowkes FG, Freedman G, Freeman MK, Gakidou E, Ghosh S, Giovannucci E, Gmel G, Graham K, Grainger R, Grant B, Gunnell D, Gutierrez HR, Hall W, Hoek HW, Hogan A, Hosgood HD, Hoy D, Hu H, Hubbell BJ, Hutchings SJ, Ibeanusi SE, Jacklyn GL, Jasrasaria R, Jonas JB, Kan H, Kanis JA, Kassebaum N, Kawakami N, Khang YH, Khatibzadeh S, Khoo JP, Kok C, Laden F, Lalloo R, Lan Q, Lathlean T, Leasher JL, Leigh J, Li Y, Lin JK, Lipshultz SE, London S, Lozano R, Lu Y, Mak J, Malekzadeh R, Mallinger L, Marcenes W, March L, Marks R, Martin R, McGale P, McGrath J, Mehta S, Mensah GA, Merriman TR, Micha R, Michaud C, Mishra V, Mohd Hanafiah K, Mokdad AA, Morawska L, Mozaffarian D, Murphy T, Naghavi M, Neal B, Nelson PK, Nolla JM, Norman R, Olives C, Omer SB, Orchard J, Osborne R, Ostro B, Page A, Pandey KD, Parry CD, Passmore E, Patra J, Pearce N, Pelizzari PM, Petzold M, Phillips MR, Pope D, Pope CA, Powles J, Rao M, Razavi H, Rehfuess EA, Rehm JT, Ritz B, Rivara FP, Roberts T, Robinson C, Rodriguez-Portales JA, Romieu I, Room R, Rosenfeld LC, Roy A, Rushton L, Salomon JA, Sampson U, Sanchez-Riera L, Sanman E, Sapkota A, Seedat S, Shi P, Shield K, Shivakoti R, Singh GM, Sleet DA, Smith E, Smith KR, Stapelberg NJ, Steenland K, Stöckl H, Stovner LJ, Straif K, Straney L, Thurston GD, Tran JH, Van Dingenen R, van Donkelaar A, Veerman JL, Vijayakumar L, Weintraub R, Weissman MM, White RA, Whiteford H, Wiersma ST, Wilkinson JD, Williams HC, Williams W, Wilson N, Woolf AD, Yip P, Zielinski JM, Lopez AD, Murray CJ, Ezzati M, AlMazroa MA, Memish ZA. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012 Dec 15; 380(9859):2224-60.

Trupin L, Katz PP, Balmes JR, Chen H, Yelin EH, Omachi T, Blanc PD. Mediators of the socioeconomic gradient in outcomes of adult asthma and rhinitis. Am J Public Health. 2013 Feb; 103(2):e31-8.

Thurston GD, Balmes JR. Particulate matter and the environmental protection agency: setting the right standard. Am J Respir Cell Mol Biol. 2012 Dec; 47(6):727-8.

Mortimer K, Gordon SB, Jindal SK, Accinelli RA, Balmes J, Martin WJ. Household air pollution is a major avoidable risk factor for cardiorespiratory disease. Chest. 2012 Nov; 142(5):1308-15.

Diette GB, Accinelli RA, Balmes JR, Buist AS, Checkley W, Garbe P, Hansel NN, Kapil V, Gordon S, Lagat DK, Yip F, Mortimer K, Perez-Padilla R, Roth C, Schwaninger JM, Punturieri A, Kiley J. OBSTRUCTIVE LUNG DISEASE AND EXPOSURE TO BURNING BIOMASS FUEL IN THE INDOOR ENVIRONMENT. Glob Heart. 2012 Sep 1; 7(3):265-270.

St Helen G, Holland NT, Balmes JR, Hall DB, Bernert JT, Vena JE, Wang JS, Naeher LP. Utility of urinary Clara cell protein (CC16) to demonstrate increased lung epithelial permeability in non-smokers exposed to outdoor secondhand smoke. J Expo Sci Environ Epidemiol. 2013 Mar; 23(2):183-9.

Frey PF, Ganz P, Hsue PY, Benowitz NL, Glantz SA, Balmes JR, Schick SF. The exposure-dependent effects of aged secondhand smoke on endothelial function. J Am Coll Cardiol. 2012 May 22; 59(21):1908-13.

Gale SL, Noth EM, Mann J, Balmes J, Hammond SK, Tager IB. Polycyclic aromatic hydrocarbon exposure and wheeze in a cohort of children with asthma in Fresno, CA. J Expo Sci Environ Epidemiol. 2012 Jul; 22(4):386-92.

St Helen G, Bernert JT, Hall DB, Sosnoff CS, Xia Y, Balmes JR, Vena JE, Wang JS, Holland NT, Naeher LP. Exposure to secondhand smoke outside of a bar and a restaurant and tobacco exposure biomarkers in nonsmokers. Environ Health Perspect. 2012 Jul; 120(7):1010-6.

Donde A, Wong H, Frelinger J, Power K, Balmes JR, Arjomandi M. Effects of exercise on systemic inflammatory, coagulatory, and cardiac autonomic parameters in an inhalational exposure study. J Occup Environ Med. 2012 Apr; 54(4):466-70.

Shusterman DJ, Weaver EM, Goldberg AN, Schick SF, Wong HH, Balmes JR. Pilot evaluation of the nasal nitric oxide response to humming as an index of osteomeatal patency. Am J Rhinol Allergy. 2012 Mar-Apr; 26(2):123-6.

Pinkerton KE, Rom WN, Akpinar-Elci M, Balmes JR, Bayram H, Brandli O, Hollingsworth JW, Kinney PL, Margolis HG, Martin WJ, Sasser EN, Smith KR, Takaro TK. An official American Thoracic Society workshop report: Climate change and human health. Proc Am Thorac Soc. 2012 Mar; 9(1):3-8.

Reid CE, Mann JK, Alfasso R, English PB, King GC, Lincoln RA, Margolis HG, Rubado DJ, Sabato JE, West NL, Woods B, Navarro KM, Balmes JR. Evaluation of a heat vulnerability index on abnormally hot days: an environmental public health tracking study. Environ Health Perspect. 2012 May; 120(5):715-20.

Beckerman BS, Jerrett M, Finkelstein M, Kanaroglou P, Brook JR, Arain MA, Sears MR, Stieb D, Balmes J, Chapman K. The association between chronic exposure to traffic-related air pollution and ischemic heart disease. J Toxicol Environ Health A. 2012; 75(7):402-11.

Balmes J, Pinkerton K. Clearing the air. Am J Respir Crit Care Med. 2012 Jan 1; 185(1):1-2.

Smith KR, McCracken JP, Weber MW, Hubbard A, Jenny A, Thompson LM, Balmes J, Diaz A, Arana B, Bruce N. Effect of reduction in household air pollution on childhood pneumonia in Guatemala (RESPIRE): a randomised controlled trial. Lancet. 2011 Nov 12; 378(9804):1717-26.

Dix-Cooper L, Eskenazi B, Romero C, Balmes J, Smith KR. Neurodevelopmental performance among school age children in rural Guatemala is associated with prenatal and postnatal exposure to carbon monoxide, a marker for exposure to woodsmoke. Neurotoxicology. 2012 Mar; 33(2):246-54.

Katz P, Chen H, Omachi TA, Gregorich SE, Julian L, Cisternas M, Balmes J, Blanc PD. The role of physical inactivity in increasing disability among older adults with obstructive airway disease. J Cardiopulm Rehabil Prev. 2011 May-Jun; 31(3):193-7.

Chen H, Cisternas MG, Katz PP, Omachi TA, Trupin L, Yelin EH, Balmes JR, Blanc PD. Evaluating quality of life in patients with asthma and rhinitis: English adaptation of the rhinasthma questionnaire. Ann Allergy Asthma Immunol. 2011 Feb; 106(2):110-118.e1.

Balmes JR. How does diesel exhaust impact asthma? Thorax. 2011 Jan; 66(1):4-6.

Dauphiné DC, Ferreccio C, Guntur S, Yuan Y, Hammond SK, Balmes J, Smith AH, Steinmaus C. Lung function in adults following in utero and childhood exposure to arsenic in drinking water: preliminary findings. Int Arch Occup Environ Health. 2011 Aug; 84(6):591-600.

Nadeau K, McDonald-Hyman C, Noth EM, Pratt B, Hammond SK, Balmes J, Tager I. Ambient air pollution impairs regulatory T-cell function in asthma. J Allergy Clin Immunol. 2010 Oct; 126(4):845-852.e10.

Eisner MD, Anthonisen N, Coultas D, Kuenzli N, Perez-Padilla R, Postma D, Romieu I, Silverman EK, Balmes JR. An official American Thoracic Society public policy statement: Novel risk factors and the global burden of chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2010 Sep 1; 182(5):693-718.

Mann JK, Balmes JR, Bruckner TA, Mortimer KM, Margolis HG, Pratt B, Hammond SK, Lurmann FW, Tager IB. Short-term effects of air pollution on wheeze in asthmatic children in Fresno, California. Environ Health Perspect. 2010 Oct; 118(10):1497-502.

Arjomandi M, Seward J, Gotway MB, Nishimura S, Fulton GP, Thundiyil J, King TE, Harber P, Balmes JR. Low prevalence of chronic beryllium disease among workers at a nuclear weapons research and development facility. J Occup Environ Med. 2010 Jun; 52(6):647-52.

Trupin L, Balmes JR, Chen H, Eisner MD, Hammond SK, Katz PP, Lurmann F, Quinlan PJ, Thorne PS, Yelin EH, Blanc PD. An integrated model of environmental factors in adult asthma lung function and disease severity: a cross-sectional study. Environ Health. 2010; 9:24.

Balmes JR. When smoke gets in your lungs. Proc Am Thorac Soc. 2010 May; 7(2):98-101.

Dey R, Van Winkle L, Ewart G, Balmes J, Pinkerton K. A second chance. Setting a protective ozone standard. Am J Respir Crit Care Med. 2010 Feb 15; 181(4):297-9.

Noonan CW, Balmes JR. Biomass smoke exposures: health outcomes measures and study design. Inhal Toxicol. 2010 Feb; 22(2):108-12.

Meng YY, Rull RP, Wilhelm M, Lombardi C, Balmes J, Ritz B. Outdoor air pollution and uncontrolled asthma in the San Joaquin Valley, California. J Epidemiol Community Health. 2010 Feb; 64(2):142-7.

Brown LK, Angus DC, Marin MG, Balmes JR, Barker AF, Ewart G, Halbower AC, Lutz PO, Mularski RA, Nathanson IT, Sanders MH, Stewart GL, Upson DJ. An official American thoracic society statement: position statement on ATS activities for the promotion of respiratory and sleep/wake health and the care of the critically ill in the United States. Am J Respir Crit Care Med. 2009 Nov 15; 180(10):1023-9.

Balmes JR. Can traffic-related air pollution cause asthma? Thorax. 2009 Aug; 64(8):646-7.

Eisner MD, Jacob P, Benowitz NL, Balmes J, Blanc PD. Longer term exposure to secondhand smoke and health outcomes in COPD: impact of urine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol. Nicotine Tob Res. 2009 Aug; 11(8):945-53.

Blanc PD, Eisner MD, Earnest G, Trupin L, Balmes JR, Yelin EH, Gregorich SE, Katz PP. Further exploration of the links between occupational exposure and chronic obstructive pulmonary disease. J Occup Environ Med. 2009 Jul; 51(7):804-10.

Banks DE, Shi R, McLarty J, Cowl CT, Smith D, Tarlo SM, Daroowalla F, Balmes J, Baumann M. American College of Chest Physicians consensus statement on the respiratory health effects of asbestos. Results of a Delphi study. Chest. 2009 Jun; 135(6):1619-27.

Margolis HG, Mann JK, Lurmann FW, Mortimer KM, Balmes JR, Hammond SK, Tager IB. Altered pulmonary function in children with asthma associated with highway traffic near residence. Int J Environ Health Res. 2009 Apr; 19(2):139-55.

Harber P, Bansal S, Balmes J. Progression from beryllium exposure to chronic beryllium disease: an analytic model. Environ Health Perspect. 2009 Jun; 117(6):970-4.

Balmes JR, Earnest G, Katz PP, Yelin EH, Eisner MD, Chen H, Trupin L, Lurmann F, Blanc PD. Exposure to traffic: lung function and health status in adults with asthma. J Allergy Clin Immunol. 2009 Mar; 123(3):626-31.

Mortimer K, Neugebauer R, Lurmann F, Alcorn S, Balmes J, Tager I. Early-lifetime exposure to air pollution and allergic sensitization in children with asthma. J Asthma. 2008 Dec; 45(10):874-81.

Power KL, Balmes J, Solomon C. Controlled exposure to combined particles and ozone decreases heart rate variability. J Occup Environ Med. 2008 Nov; 50(11):1253-60.

Quinlan PJ, Earnest G, Eisner MD, Yelin EH, Katz PP, Balmes JR, Blanc PD. Performance of self-reported occupational exposure compared to a job-exposure matrix approach in asthma and chronic rhinitis. Occup Environ Med. 2009 Mar; 66(3):154-60.

Wilhelm M, Meng YY, Rull RP, English P, Balmes J, Ritz B. Environmental public health tracking of childhood asthma using California health interview survey, traffic, and outdoor air pollution data. Environ Health Perspect. 2008 Sep; 116(9):1254-60.

Tarlo SM, Balmes J, Balkissoon R, Beach J, Beckett W, Bernstein D, Blanc PD, Brooks SM, Cowl CT, Daroowalla F, Harber P, Lemiere C, Liss GM, Pacheco KA, Redlich CA, Rowe B, Heitzer J. Diagnosis and management of work-related asthma: American College Of Chest Physicians Consensus Statement. Chest. 2008 Sep; 134(3 Suppl):1S-41S.

Blanc PD, Iribarren C, Trupin L, Earnest G, Katz PP, Balmes J, Sidney S, Eisner MD. Occupational exposures and the risk of COPD: dusty trades revisited. Thorax. 2009 Jan; 64(1):6-12.

Mortimer K, Neugebauer R, Lurmann F, Alcorn S, Balmes J, Tager I. Air pollution and pulmonary function in asthmatic children: effects of prenatal and lifetime exposures. Epidemiology. 2008 Jul; 19(4):550-7; discussion 561-2.

Heiss C, Amabile N, Lee AC, Real WM, Schick SF, Lao D, Wong ML, Jahn S, Angeli FS, Minasi P, Springer ML, Hammond SK, Glantz SA, Grossman W, Balmes JR, Yeghiazarians Y. Brief secondhand smoke exposure depresses endothelial progenitor cells activity and endothelial function: sustained vascular injury and blunted nitric oxide production. J Am Coll Cardiol. 2008 May 6; 51(18):1760-71.

Arjomandi M, Tager IB, Bastaki M, Chen C, Holland N, Balmes JR. Is there an association between lifetime cumulative exposure and acute pulmonary responses to ozone? J Occup Environ Med. 2008 Mar; 50(3):341-9.

Blanc PD, Eisner MD, Yelin EH, Earnest G, Balmes JR, Gregorich SE, Katz PP. Socioeconomic gradients in tiotropium use among adults with COPD. Int J Chron Obstruct Pulmon Dis. 2008; 3(3):483-90.

Chen C, Arjomandi M, Balmes J, Tager I, Holland N. Effects of chronic and acute ozone exposure on lipid peroxidation and antioxidant capacity in healthy young adults. Environ Health Perspect. 2007 Dec; 115(12):1732-7.

Torén K, Balmes J. Chronic obstructive pulmonary disease: does occupation matter? Am J Respir Crit Care Med. 2007 Nov 15; 176(10):951-2.

Chen C, Arjomandi M, Tager IB, Holland N, Balmes JR. Effects of antioxidant enzyme polymorphisms on ozone-induced lung function changes. Eur Respir J. 2007 Oct; 30(4):677-83.

Pinkerton KE, Balmes JR, Fanucchi MV, Rom WN. Ozone, a malady for all ages. Am J Respir Crit Care Med. 2007 Jul 15; 176(2):107-8.

Thompson L, Diaz J, Jenny A, Diaz A, Bruce N, Balmes J. Nxwisen, ntzarrin or ntzo'lin? Mapping children's respiratory symptoms among indigenous populations in Guatemala. Soc Sci Med. 2007 Oct; 65(7):1337-50.

Eisner MD, Wang Y, Haight TJ, Balmes J, Hammond SK, Tager IB. Secondhand smoke exposure, pulmonary function, and cardiovascular mortality. Ann Epidemiol. 2007 May; 17(5):364-73.

Blanc PD, Balmes JR. Epidemiology and costs of COPD. Eur Respir J. 2006 Dec; 28(6):1290.

Balmes JR. The World Trade Center collapse: a continuing tragedy for lung health? Am J Respir Crit Care Med. 2006 Aug 1; 174(3):235-6.

Kyle AD, Balmes JR, Buffler PA, Lee PR. Integrating research, surveillance, and practice in environmental public health tracking. Environ Health Perspect. 2006 Jul; 114(7):980-4.

Eisner MD, Balmes J, Yelin EH, Katz PP, Hammond SK, Benowitz N, Blanc PD. Directly measured secondhand smoke exposure and COPD health outcomes. BMC Pulm Med. 2006; 6:12.

Diaz JV, Koff J, Gotway MB, Nishimura S, Balmes JR. Case report: a case of wood-smoke-related pulmonary disease. Environ Health Perspect. 2006 May; 114(5):759-62.

Bastaki M, Huen K, Manzanillo P, Chande N, Chen C, Balmes JR, Tager IB, Holland N. Genotype-activity relationship for Mn-superoxide dismutase, glutathione peroxidase 1 and catalase in humans. Pharmacogenet Genomics. 2006 Apr; 16(4):279-86.

Chen C, Arjomandi M, Qin H, Balmes J, Tager I, Holland N. Cytogenetic damage in buccal epithelia and peripheral lymphocytes of young healthy individuals exposed to ozone. Mutagenesis. 2006 Mar; 21(2):131-7.

Brodkin CA, Balmes JR, Redlich CA, Cullen MR. Residential proximity to naturally occurring asbestos: health risk or ecologic fallacy? Am J Respir Crit Care Med. 2006 Mar 1; 173(5):573; author reply 573-4.

Yelin E, Katz P, Balmes J, Trupin L, Earnest G, Eisner M, Blanc P. Work life of persons with asthma, rhinitis, and COPD: a study using a national, population-based sample. J Occup Med Toxicol. 2006; 1:2.

Tujague J, Bastaki M, Holland N, Balmes JR, Tager IB. Antioxidant intake, GSTM1 polymorphism and pulmonary function in healthy young adults. Eur Respir J. 2006 Feb; 27(2):282-8.

Ratto J, Wong H, Liu J, Fahy J, Boushey H, Solomon C, Balmes J. Effects of multiday exposure to ozone on airway inflammation as determined using sputum induction. Environ Health Perspect. 2006 Feb; 114(2):209-12.

Blanc PD, Yen IH, Chen H, Katz PP, Earnest G, Balmes JR, Trupin L, Friedling N, Yelin EH, Eisner MD. Area-level socio-economic status and health status among adults with asthma and rhinitis. Eur Respir J. 2006 Jan; 27(1):85-94.

Witten A, Solomon C, Abbritti E, Arjomandi M, Zhai W, Kleinman M, Balmes J. Effects of nitrogen dioxide on allergic airway responses in subjects with asthma. J Occup Environ Med. 2005 Dec; 47(12):1250-9.

Mazumder DN, Steinmaus C, Bhattacharya P, von Ehrenstein OS, Ghosh N, Gotway M, Sil A, Balmes JR, Haque R, Hira-Smith MM, Smith AH. Bronchiectasis in persons with skin lesions resulting from arsenic in drinking water. Epidemiology. 2005 Nov; 16(6):760-5.

Tager IB, Balmes J, Lurmann F, Ngo L, Alcorn S, Künzli N. Chronic exposure to ambient ozone and lung function in young adults. Epidemiology. 2005 Nov; 16(6):751-9.

Katz PP, Eisner MD, Yelin EH, Trupin L, Earnest G, Balmes J, Blanc PD. Functioning and psychological status among individuals with COPD. Qual Life Res. 2005 Oct; 14(8):1835-43.

Aliyu OA, Cullen MR, Barnett MJ, Balmes JR, Cartmel B, Redlich CA, Brodkin CA, Barnhart S, Rosenstock L, Israel L, Goodman GE, Thornquist MD, Omenn GS. Evidence for excess colorectal cancer incidence among asbestos-exposed men in the Beta-Carotene and Retinol Efficacy Trial. Am J Epidemiol. 2005 Nov 1; 162(9):868-78.

von Ehrenstein OS, Mazumder DN, Yuan Y, Samanta S, Balmes J, Sil A, Ghosh N, Hira-Smith M, Haque R, Purushothamam R, Lahiri S, Das S, Smith AH. Decrements in lung function related to arsenic in drinking water in West Bengal, India. Am J Epidemiol. 2005 Sep 15; 162(6):533-41.

Blanc PD, Eisner MD, Balmes JR, Trupin L, Yelin EH, Katz PP. Exposure to vapors, gas, dust, or fumes: assessment by a single survey item compared to a detailed exposure battery and a job exposure matrix. Am J Ind Med. 2005 Aug; 48(2):110-7.

Hammond SK, Gold E, Baker R, Quinlan P, Smith W, Pandya R, Balmes J. Respiratory health effects related to occupational spray painting and welding. J Occup Environ Med. 2005 Jul; 47(7):728-39.

Arjomandi M, Schmidlin I, Girling P, Boylen K, Ferrando R, Balmes J. Sputum induction and bronchoscopy for assessment of ozone-induced airway inflammation in asthma. Chest. 2005 Jul; 128(1):416-23.

Arjomandi M, Witten A, Abbritti E, Reintjes K, Schmidlin I, Zhai W, Solomon C, Balmes J. Repeated exposure to ozone increases alveolar macrophage recruitment into asthmatic airways. Am J Respir Crit Care Med. 2005 Aug 15; 172(4):427-32.

Eisner MD, Trupin L, Katz PP, Yelin EH, Earnest G, Balmes J, Blanc PD. Development and validation of a survey-based COPD severity score. Chest. 2005 Jun; 127(6):1890-7.

Eisner MD, Balmes J, Katz PP, Trupin L, Yelin EH, Blanc PD. Lifetime environmental tobacco smoke exposure and the risk of chronic obstructive pulmonary disease. Environ Health. 2005; 4(1):7.

Blanc PD, Eisner MD, Katz PP, Yen IH, Archea C, Earnest G, Janson S, Masharani UB, Quinlan PJ, Hammond SK, Thorne PS, Balmes JR, Trupin L, Yelin EH. Impact of the home indoor environment on adult asthma and rhinitis. J Occup Environ Med. 2005 Apr; 47(4):362-72.

Ritz B, Tager I, Balmes J. Can lessons from public health disease surveillance be applied to environmental public health tracking? Environ Health Perspect. 2005 Mar; 113(3):243-9.

Cullen MR, Barnett MJ, Balmes JR, Cartmel B, Redlich CA, Brodkin CA, Barnhart S, Rosenstock L, Goodman GE, Hammar SP, Thornquist MD, Omenn GS. Predictors of lung cancer among asbestos-exposed men in the {beta}-carotene and retinol efficacy trial. Am J Epidemiol. 2005 Feb 1; 161(3):260-70.

Balmes JR. Occupational contribution to the burden of chronic obstructive pulmonary disease. J Occup Environ Med. 2005 Feb; 47(2):154-60.

Goodman GE, Thornquist MD, Balmes J, Cullen MR, Meyskens FL, Omenn GS, Valanis B, Williams JH. The Beta-Carotene and Retinol Efficacy Trial: incidence of lung cancer and cardiovascular disease mortality during 6-year follow-up after stopping beta-carotene and retinol supplements. J Natl Cancer Inst. 2004 Dec 1; 96(23):1743-50.

Shusterman D, Balmes J, Murphy MA, Tai CF, Baraniuk J. Chlorine inhalation produces nasal airflow limitation in allergic rhinitic subjects without evidence of neuropeptide release. Neuropeptides. 2004 Dec; 38(6):351-8.

Blanc PD, Eisner MD, Trupin L, Yelin EH, Katz PP, Balmes JR. The association between occupational factors and adverse health outcomes in chronic obstructive pulmonary disease. Occup Environ Med. 2004 Aug; 61(8):661-7.

Shusterman D, Murphy MA, Balmes J. Influence of age, gender, and allergy status on nasal reactivity to inhaled chlorine. Inhal Toxicol. 2003 Oct; 15(12):1179-89.

Trupin L, Earnest G, San Pedro M, Balmes JR, Eisner MD, Yelin E, Katz PP, Blanc PD. The occupational burden of chronic obstructive pulmonary disease. Eur Respir J. 2003 Sep; 22(3):462-9.

Shusterman D, Murphy MA, Balmes J. Differences in nasal irritant sensitivity by age, gender, and allergic rhinitis status. Int Arch Occup Environ Health. 2003 Oct; 76(8):577-83.

Mortimer KM, Fallot A, Balmes JR, Tager IB. Evaluating the use of a portable spirometer in a study of pediatric asthma. Chest. 2003 Jun; 123(6):1899-907.

Shusterman D, Balmes J, Avila PC, Murphy MA, Matovinovic E. Chlorine inhalation produces nasal congestion in allergic rhinitics without mast cell degranulation. Eur Respir J. 2003 Apr; 21(4):652-7.

Balmes J, Becklake M, Blanc P, Henneberger P, Kreiss K, Mapp C, Milton D, Schwartz D, Toren K, Viegi G. American Thoracic Society Statement: Occupational contribution to the burden of airway disease. Am J Respir Crit Care Med. 2003 Mar 1; 167(5):787-97.

Balmes JR. Occupational airways diseases from chronic low-level exposures to irritants. Clin Chest Med. 2002 Dec; 23(4):727-35, vi.

Gotway MB, Golden JA, Warnock M, Koth LL, Webb R, Reddy GP, Balmes JR. Hard metal interstitial lung disease: high-resolution computed tomography appearance. J Thorac Imaging. 2002 Oct; 17(4):314-8.

Shusterman D, Murphy MA, Walsh P, Balmes JR. Cholinergic blockade does not alter the nasal congestive response to irritant provocation. Rhinology. 2002 Sep; 40(3):141-6.

Zitter JN, Mazonson PD, Miller DP, Hulley SB, Balmes JR. Aircraft cabin air recirculation and symptoms of the common cold. JAMA. 2002 Jul 24-31; 288(4):483-6.

Pandya RJ, Solomon G, Kinner A, Balmes JR. Diesel exhaust and asthma: hypotheses and molecular mechanisms of action. Environ Health Perspect. 2002 Feb; 110 Suppl 1:103-12.

Shusterman D, Solomon C, Balmes J, Blanc P. Chlorine exposure and the upper respiratory tract. Eur Respir J. 2002 Feb; 19(2):381-2.

Shusterman D, Murphy MA, Balmes J. The influence of sex, allergic rhinitis, and test system on nasal sensitivity to airborne irritants: a pilot study. Environ Health Perspect. 2001 Jan; 109(1):15-9.

Reinisch F, Harrison RJ, Cussler S, Athanasoulis M, Balmes J, Blanc P, Cone J. Physician reports of work-related asthma in California, 1993-1996. Am J Ind Med. 2001 Jan; 39(1):72-83.

Balmes JR. Occupational respiratory diseases. Prim Care. 2000 Dec; 27(4):1009-38.

Steinmaus C, Balmes JR. Government laboratory worker with lung cancer: comparing risks from beryllium, asbestos, and tobacco smoke. Environ Health Perspect. 2000 Oct; 108(10):1003-6.

Lombardo LJ, Balmes JR. Occupational asthma: a review. Environ Health Perspect. 2000 Aug; 108 Suppl 4:697-704.

Criqui GI, Solomon C, Welch BS, Ferrando RE, Boushey HA, Balmes JR. Effects of azithromycin on ozone-induced airway neutrophilia and cytokine release. Eur Respir J. 2000 May; 15(5):856-62.

Solomon C, Christian DL, Chen LL, Welch BS, Kleinman MT, Dunham E, Erle DJ, Balmes JR. Effect of serial-day exposure to nitrogen dioxide on airway and blood leukocytes and lymphocyte subsets. Eur Respir J. 2000 May; 15(5):922-8.

Welch LS, Hunting KL, Balmes J, Bresnitz EA, Guidotti TL, Lockey JE, Myo-Lwin T. Variability in the classification of radiographs using the 1980 International Labor Organization Classification for Pneumoconioses. Chest. 1998 Dec; 114(6):1740-8.

Pappas GP, Brodkin CA, Sheppard L, Balmes J, Horike M, Barnhart S. The validity of radiographic estimation of total lung capacity in patients with respiratory disease. Chest. 1998 Aug; 114(2):513-20.

Christian DL, Chen LL, Scannell CH, Ferrando RE, Welch BS, Balmes JR. Ozone-induced inflammation is attenuated with multiday exposure. Am J Respir Crit Care Med. 1998 Aug; 158(2):532-7.

Shusterman DJ, Murphy MA, Balmes JR. Subjects with seasonal allergic rhinitis and nonrhinitic subjects react differentially to nasal provocation with chlorine gas. J Allergy Clin Immunol. 1998 Jun; 101(6 Pt 1):732-40.

Forastiere F, Balmes J, Scarinci M, Tager IB. Occupation, asthma, and chronic respiratory symptoms in a community sample of older women. Am J Respir Crit Care Med. 1998 Jun; 157(6 Pt 1):1864-70.

Tager IB, Künzli N, Ngo L, Balmes J. Methods development for epidemiologic investigations of the health effects of prolonged ozone exposure. Part I: Variability of pulmonary function measures. Res Rep Health Eff Inst. 1998 Mar; (81):1-25; discussion 109-21.

Tager IB, Künzli N, Lurmann F, Ngo L, Segal M, Balmes J. Methods development for epidemiologic investigations of the health effects of prolonged ozone exposure. Part II. An approach to retrospective estimation of lifetime ozone exposure using a questionnaire and ambient monitoring data (California sites). Res Rep Health Eff Inst. 1998 Mar; (81):27-78; discussion 109-21.

Künzli N, Kelly T, Balmes J, Tager IB. Reproducibility of retrospective assessment of outdoor time-activity patterns as an individual determinant of long-term ambient ozone exposure. Int J Epidemiol. 1997 Dec; 26(6):1258-71.

Barnhart S, Keogh J, Cullen MR, Brodkin C, Liu D, Goodman G, Valanis B, Glass A, Thornquist M, Rosenstock L, Omenn G, Balmes J. The CARET asbestos-exposed cohort: baseline characteristics and comparison to other asbestos-exposed cohorts. Am J Ind Med. 1997 Dec; 32(6):573-81.

Brodkin CA, McCullough J, Stover B, Balmes J, Hammar S, Omenn GS, Checkoway H, Barnhart S. Lobe of origin and histologic type of lung cancer associated with asbestos exposure in the Carotene and Retinol Efficacy Trial (CARET). Am J Ind Med. 1997 Dec; 32(6):582-91.

Shusterman DJ, Balmes JR. A comparison of two methods for determining nasal irritant sensitivity. Am J Rhinol. 1997 Sep-Oct; 11(5):371-8.

Barnhart S, Sheppard L, Beaudet N, Stover B, Balmes J. Tuberculosis in health care settings and the estimated benefits of engineering controls and respiratory protection. J Occup Environ Med. 1997 Sep; 39(9):849-54.

Shusterman D, Balmes J. Measurement of nasal irritant sensitivity to pulsed carbon dioxide: a pilot study. Arch Environ Health. 1997 Sep-Oct; 52(5):334-40.

Frampton MW, Balmes JR, Cox C, Krein PM, Speers DM, Tsai Y, Utell MJ. Effects of ozone on normal and potentially sensitive human subjects. Part III: Mediators of inflammation in bronchoalveolar lavage fluid from nonsmokers, smokers, and asthmatic subjects exposed to ozone: a collaborative study. Res Rep Health Eff Inst. 1997 Jun; (78):73-9; discussion 81-99.

Balmes JR, Aris RM, Chen LL, Scannell C, Tager IB, Finkbeiner W, Christian D, Kelly T, Hearne PQ, Ferrando R, Welch B. Effects of ozone on normal and potentially sensitive human subjects. Part I: Airway inflammation and responsiveness to ozone in normal and asthmatic subjects. Res Rep Health Eff Inst. 1997 Jun; (78):1-37; discussion 81-99.

Chuwers P, Barnhart S, Blanc P, Brodkin CA, Cullen M, Kelly T, Keogh J, Omenn G, Williams J, Balmes JR. The protective effect of beta-carotene and retinol on ventilatory function in an asbestos-exposed cohort. Am J Respir Crit Care Med. 1997 Mar; 155(3):1066-71.

Künzli N, Lurmann F, Segal M, Ngo L, Balmes J, Tager IB. Association between lifetime ambient ozone exposure and pulmonary function in college freshmen--results of a pilot study. Environ Res. 1997 Jan; 72(1):8-23.

Omenn GS, Goodman GE, Thornquist MD, Balmes J, Cullen MR, Glass A, Keogh JP, Meyskens FL, Valanis B, Williams JH, Barnhart S, Cherniack MG, Brodkin CA, Hammar S. Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial. J Natl Cancer Inst. 1996 Nov 6; 88(21):1550-9.

Wang A, Yokosaki Y, Ferrando R, Balmes J, Sheppard D. Differential regulation of airway epithelial integrins by growth factors. Am J Respir Cell Mol Biol. 1996 Nov; 15(5):664-72.

Künzli N, Lurman F, Segal M, Ngo L, Balmes J, Tager IB. Reliability of lifetime residential history and activity measures as elements of cumulative ambient ozone exposure assessment. J Expo Anal Environ Epidemiol. 1996 Jul-Sep; 6(3):289-310.

Scannell C, Chen L, Aris RM, Tager I, Christian D, Ferrando R, Welch B, Kelly T, Balmes JR. Greater ozone-induced inflammatory responses in subjects with asthma. Am J Respir Crit Care Med. 1996 Jul; 154(1):24-9.

Omenn GS, Goodman GE, Thornquist MD, Balmes J, Cullen MR, Glass A, Keogh JP, Meyskens FL, Valanis B, Williams JH, Barnhart S, Hammar S. Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease. N Engl J Med. 1996 May 2; 334(18):1150-5.

Balmes JR, Chen LL, Scannell C, Tager I, Christian D, Hearne PQ, Kelly T, Aris RM. Ozone-induced decrements in FEV1 and FVC do not correlate with measures of inflammation. Am J Respir Crit Care Med. 1996 Mar; 153(3):904-9.

Omenn GS, Goodman G, Thornquist M, Barnhart S, Balmes J, Cherniack M, Cullen M, Glass A, Keogh J, Liu D, Meyskens F, Perloff M, Valanis B, Williams J. Chemoprevention of lung cancer: the beta-Carotene and Retinol Efficacy Trial (CARET) in high-risk smokers and asbestos-exposed workers. IARC Sci Publ. 1996; (136):67-85.

Brodkin CA, Barnhart S, Checkoway H, Balmes J, Omenn GS, Rosenstock L. Longitudinal pattern of reported respiratory symptoms and accelerated ventilatory loss in asbestos-exposed workers. Chest. 1996 Jan; 109(1):120-6.

Shusterman D, Alexeeff G, Hargis C, Kaplan J, Sato R, Gelb A, Becker C, Benowitz N, Gillen M, Thollaug S, Balmes J. Predictors of carbon monoxide and hydrogen cyanide exposure in smoke inhalation patients. J Toxicol Clin Toxicol. 1996; 34(1):61-71.

Nadziejko C, Finkelstein I, Balmes JR. Contribution of secretory leukocyte proteinase inhibitor to the antiprotease defense system of the peripheral lung: effect of ozone-induced acute inflammation. Am J Respir Crit Care Med. 1995 Nov; 152(5 Pt 1):1592-8.

Scannell CH, Balmes JR. Pulmonary effects of firefighting. Occup Med. 1995 Oct-Dec; 10(4):789-801.

Balmes JR. Asthma and air pollution. West J Med. 1995 Oct; 163(4):372-3.

Shusterman D, Balmes J, Cone J. Irritant-induced asthma. J Occup Environ Med. 1995 Jun; 37(6):662.

Weinacker A, Ferrando R, Elliott M, Hogg J, Balmes J, Sheppard D. Distribution of integrins alpha v beta 6 and alpha 9 beta 1 and their known ligands, fibronectin and tenascin, in human airways. Am J Respir Cell Mol Biol. 1995 May; 12(5):547-56.

Aris RM, Tager I, Christian D, Kelly T, Balmes JR. Methacholine responsiveness is not associated with O3-induced decreases in FEV1. Chest. 1995 Mar; 107(3):621-8.

Frumkin H, Gerr F, Hessl SM, Cullen M, Schwartz B, Mitchell CS, Weaver VM, Pransky G, Frank AL, Balmes J. Ethics, occupational medicine, and ACOEM. J Occup Environ Med. 1995 Feb; 37(2):127-8, 133.

Balmes JR, Estacio PL, Quinlan P, Kelly T, Corkery K, Blanc P. Respiratory effects of occupational exposure to aerosolized pentamidine. J Occup Environ Med. 1995 Feb; 37(2):145-50.

Cone JE, Wugofski L, Balmes JR, Das R, Bowler R, Alexeeff G, Shusterman D. Persistent respiratory health effects after a metam sodium pesticide spill. Chest. 1994 Aug; 106(2):500-8.

Blanc PD, Galbo M, Balmes JR, Olson KR. Occupational factors in work-related inhalations: inferences for prevention strategy. Am J Ind Med. 1994 Jun; 25(6):783-91.

Omenn GS, Goodman G, Thornquist M, Grizzle J, Rosenstock L, Barnhart S, Balmes J, Cherniack MG, Cullen MR, Glass A. The beta-carotene and retinol efficacy trial (CARET) for chemoprevention of lung cancer in high risk populations: smokers and asbestos-exposed workers. Cancer Res. 1994 Apr 1; 54(7 Suppl):2038s-2043s.

Balmes JR. The role of ozone exposure in the epidemiology of asthma. Environ Health Perspect. 1993 Dec; 101 Suppl 4:219-24.

Aris RM, Christian D, Hearne PQ, Kerr K, Finkbeiner WE, Balmes JR. Ozone-induced airway inflammation in human subjects as determined by airway lavage and biopsy. Am Rev Respir Dis. 1993 Nov; 148(5):1363-72.

Aris R, Christian D, Tager I, Ngo L, Finkbeiner WE, Balmes JR. Effects of nitric acid gas alone or in combination with ozone on healthy volunteers. Am Rev Respir Dis. 1993 Oct; 148(4 Pt 1):965-73.

Thornquist MD, Omenn GS, Goodman GE, Grizzle JE, Rosenstock L, Barnhart S, Anderson GL, Hammar S, Balmes J, Cherniack M. Statistical design and monitoring of the Carotene and Retinol Efficacy Trial (CARET). Control Clin Trials. 1993 Aug; 14(4):308-24.

Blanc PD, Galbo M, Hiatt P, Olson KR, Balmes JR. Symptoms, lung function, and airway responsiveness following irritant inhalation. Chest. 1993 Jun; 103(6):1699-705.

Royce S, Wald P, Sheppard D, Balmes J. Occupational asthma in a pesticides manufacturing worker. Chest. 1993 Jan; 103(1):295-6.

Liu D, Tager IB, Balmes JR, Harrison RJ. The effect of smoke inhalation on lung function and airway responsiveness in wildland fire fighters. Am Rev Respir Dis. 1992 Dec; 146(6):1469-73.

Balmes JR. To B-read or not to B-read. J Occup Med. 1992 Sep; 34(9):885-6.

Balmes JR. Occupational asthma. West J Med. 1992 Aug; 157(2):169.

Omenn GS, Goodman G, Grizzle J, Thornquist M, Rosenstock L, Barnhart S, Anderson G, Balmes J, Cone J, Cherniack M. Recruitment for the beta-carotene and retinol efficacy trial (CARET) to prevent lung cancer in smokers and asbestos-exposed workers. West J Med. 1992 May; 156(5):540-4.

Markowitz S, Frank AL, Hessl SM, Christiani D, Robins T, Balmes J. Physicians and occupational medicine. N Engl J Med. 1992 Mar 5; 326(10):713-4.

Das R, Tager IB, Gamsky T, Schenker MB, Royce S, Balmes JR. Atopy and airways reactivity in animal health technicians. A pilot study. J Occup Med. 1992 Jan; 34(1):53-60.

Balmes J, Rempel D, Alexander M, Reiter R, Harrison R, Bernard B, Benner D, Cone J. Hospital records as a data source for occupational disease surveillance: a feasibility study. Am J Ind Med. 1992; 21(3):341-51.

Balmes JR, Daponte A, Cone JE. Asbestos-related disease in custodial and building maintenance workers from a large municipal school district. Ann N Y Acad Sci. 1991 Dec 31; 643:540-9.

Rempel D, Jones J, Atterbury M, Balmes J. Respiratory effects of exposure of shipyard workers to epoxy paints. Br J Ind Med. 1991 Nov; 48(11):783-7.

Balmes JR. The environmental impact of chlorofluorocarbon use in metered dose inhalers. Chest. 1991 Oct; 100(4):1101-2.

Gordon T, Balmes J, Fine J, Sheppard D. Airway oedema and obstruction in guinea pigs exposed to inhaled endotoxin. Br J Ind Med. 1991 Sep; 48(9):629-35.

Balmes JR. Propellant gases in metered dose inhalers: their impact on the global environment. Respir Care. 1991 Sep; 36(9):1037-44.

Cone JE, Daponte A, Makofsky D, Reiter R, Becker C, Harrison RJ, Balmes J. Fatal injuries at work in California. J Occup Med. 1991 Jul; 33(7):813-7.

Aris R, Christian D, Sheppard D, Balmes JR. Lack of bronchoconstrictor response to sulfuric acid aerosols and fogs. Am Rev Respir Dis. 1991 Apr; 143(4 Pt 1):744-50.

Aberle DR, Balmes JR. Computed tomography of asbestos-related pulmonary parenchymal and pleural diseases. Clin Chest Med. 1991 Mar; 12(1):115-31.

Omenn GS, Goodman G, Grizzle J, Thornquist M, Rosenstock L, Barnhart S, Anderson G, Balmes J, Cherniack M, Cone J. CARET, the beta-carotene and retinol efficacy trial to prevent lung cancer in asbestos-exposed workers and in smokers. Anticancer Drugs. 1991 Feb; 2(1):79-86.

Aris R, Christian D, Sheppard D, Balmes JR. The effects of sequential exposure to acidic fog and ozone on pulmonary function in exercising subjects. Am Rev Respir Dis. 1991 Jan; 143(1):85-91.

Balmes JR. Surveillance for occupational asthma. Occup Med. 1991 Jan-Mar; 6(1):101-10.

Klees JE, Alexander M, Rempel D, Beckett W, Rubin R, Barnhart S, Balmes JR. Evaluation of a proposed NIOSH surveillance. Case definition for occupational asthma. Chest. 1990 Nov; 98(5 Suppl):212S-215S.

Balmes JR. Medical surveillance for pulmonary endpoints. Occup Med. 1990 Jul-Sep; 5(3):499-513.

Aris R, Christian D, Sheppard D, Balmes JR. Acid fog-induced bronchoconstriction. The role of hydroxymethanesulfonic acid. Am Rev Respir Dis. 1990 Mar; 141(3):546-51.

Balmes J. Silica exposure and tuberculosis: an old problem with some new twists. J Occup Med. 1990 Feb; 32(2):114-5.

Balmes J, London SJ, Peters JM. Isocyanates, polyurethane paints, and asthma. West J Med. 1990 Feb; 152(2):172-3.

Balmes JR, Fine JM, Gordon T, Sheppard D. Potential bronchoconstrictor stimuli in acid fog. Environ Health Perspect. 1989 Feb; 79:163-6.

Uba G, Pachorek D, Bernstein J, Garabrant DH, Balmes JR, Wright WE, Amar RB. Prospective study of respiratory effects of formaldehyde among healthy and asthmatic medical students. Am J Ind Med. 1989; 15(1):91-101.

Fine JM, Balmes JR. Airway inflammation and occupational asthma. Clin Chest Med. 1988 Dec; 9(4):577-90.

Gelmont DM, Balmes JR, Yee A. Hypokalemia induced by inhaled bronchodilators. Chest. 1988 Oct; 94(4):763-6.

Bush RK, Schroeckenstein D, Meier-Davis S, Balmes J, Rempel D. Soybean flour asthma: detection of allergens by immunoblotting. J Allergy Clin Immunol. 1988 Aug; 82(2):251-5.

Shusterman D, Balmes J, Cone J. Behavioral sensitization to irritants/odorants after acute overexposures. J Occup Med. 1988 Jul; 30(7):565-7.

Balmes JR, Fine JM, Christian D, Gordon T, Sheppard D. Acidity potentiates bronchoconstriction induced by hypoosmolar aerosols. Am Rev Respir Dis. 1988 Jul; 138(1):35-9.

Ratto D, Balmes J, Boylen T, Sharma OP. Pregnancy in a woman with severe pulmonary fibrosis secondary to hard metal disease. Chest. 1988 Mar; 93(3):663-5.

Balmes JR, Fine JM, Sheppard D. Symptomatic bronchoconstriction after short-term inhalation of sulfur dioxide. Am Rev Respir Dis. 1987 Nov; 136(5):1117-21.

Balmes JR. Respiratory effects of hard-metal dust exposure. Occup Med. 1987 Apr-Jun; 2(2):327-44.

Kawamoto MM, Garabrant DH, Held J, Balmes JR, Patzman J, Dimick DV, Simonowitz JA, Bernstein L. Respiratory effects of cotton dust exposure in the cotton garnetting industry. Am J Ind Med. 1987; 11(5):505-15.

Cullen MR, Kominsky JR, Rossman MD, Cherniack MG, Rankin JA, Balmes JR, Kern JA, Daniele RP, Palmer L, Naegel GP. Chronic beryllium disease in a precious metal refinery. Clinical epidemiologic and immunologic evidence for continuing risk from exposure to low level beryllium fume. Am Rev Respir Dis. 1987 Jan; 135(1):201-8.

Wiedemann HP, Gee JB, Balmes JR, Loke J. Exercise testing in occupational lung diseases. Clin Chest Med. 1984 Mar; 5(1):157-71.

Balmes JR, Cullen MR, Henriksen E. Thoracic CT scanning in asbestos workers with lung cancer. Conn Med. 1982 Sep; 46(9):515-7.

Matthay RA, Balmes JR. Lung cancer: a persistent challenge. Geriatrics. 1982 Feb; 37(2):109-12, 117, 123-4 passim.

Balmes J, Cullen MR, Gee JB. What infections occur in patients with occupational lung disease? Clin Chest Med. 1981 Jan; 2(1):111-20.

Cullen MR, Balmes JR, Robins JM, Smith GJ. Lipoid pneumonia caused by oil mist exposure from a steel rolling tandem mill. Am J Ind Med. 1981; 2(1):51-8.

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