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Acute Lung Injury

ALI Research at UCSF. UCSF has a rich history of research on ALI that includes studies on the role of surfactant in the injured lung, research on the resolution of excess fluid (pulmonary edema) in the lung, and many studies in partnership with the National Institutes of Health’s ARDS Network, for which UCSF was one of the founding institutions. This research has led to therapies such as surfactant replacement in neonatal ALI and gentler lung ventilation that have undoubtedly saved thousands of lives. At UCSF, our group of Pulmonary and Critical Care specialists has active research programs that are taking novel approaches to the prevention, early diagnosis, and treatment of ALI. These programs include:

The research environment is intended to foster productive interactions between basic and clinical scientists. Members of the research group include fellows and faculty from the Departments of Medicine, Anesthesia, Pediatrics, and the CVRI. Several young faculty members contribute substantially to an environment to foster the growth of the next generation of pulmonary and critical care medicine investigators, as well as high quality research.

Acute Respiratory Distress Syndrome

UCSF is a major center for the clinical care of critically ill patients with ARDS (also know as Acute Lung Injury) at all the affiliated hospitals, including NIH supported basic and clinical interdisciplinary research on ARDS, UCSF also is an NIH supported center for carrying out phase II and phase III clinical trials. Several faculty members in the Departments of Medicine, Anesthesia, Surgery, and Pediatrics as well as post-doctoral fellows are focused on basic research and clinical research issues in ARDS, and related critical care issues, in both adults and children.