Leah Witt Gaspard, MD

Myers LC, Quint JK, Hawkins NM, Putcha N, Hamilton A, Lindenauer P, Wells JM, Witt LJ, Shah SP, Lee T, Nguyen H, Gainer C, Walkey A, Mannino DM, Bhatt SP, Barr RG, Mularski R, Dransfield M, Khan SS, Gershon AS, Divo M, Press VG. A Research Agenda to Improve Outcomes in Patients with Chronic Obstructive Pulmonary Disease and Cardiovascular Disease. An Official American Thoracic Society Research Statement. American journal of respiratory and critical care medicine 2024. PMID: 39133888

Iyer AS, Wells RD, Bechthold AC, Armstrong M, O'Beirne R, Byun JY, Coffee-Dunning J, Odom JN, Buhr RG, Suen AO, Kotwal AA, Witt LJ, Brown CJ, Dransfield MT, Bakitas MA. Identifying priority challenges of older adults with COPD: A multiphase intervention refinement study. Journal of the American Geriatrics Society 2024. PMID: 39215557

Witt LJ, Heath JK. Ambulatory Blocks in Pulmonary and Critical Care Fellowship Reprioritize Outpatient Medicine. ATS Scholar 2024. PMID: 38957488

Suen AO, Cenzer I, Iyer AS, Witt LJ, Smith AK, Kotwal A. The National Prevalence of Supplemental Oxygen Use in Persons with Chronic Obstructive Pulmonary Disease: A Comparison of Claims-based and Self-reported Supplemental Oxygen Use. Annals of the American Thoracic Society 2024. PMID: 38330174

Wang E, Wroblewski KE, McClintock MK, Witt LJ, Pinto JM. Examining the Longitudinal Relationship Between Olfactory Dysfunction and Frailty in Community-Dwelling, older US Adults. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2024. PMID: 38660882

Wang E, Wroblewski KE, McClintock MK, Pinto JM, Witt LJ. Olfactory decline develops in parallel with frailty in older US adults with obstructive lung diseases. International forum of allergy & rhinology 2023. PMID: 37747949

Expert Panel on Thoracic Imaging, Sandler KL, Henry TS, Amini A, Elojeimy S, Kelly AM, Kuzniewski CT, Lee E, Martin MD, Morris MF, Peterson NB, Raptis CA, Silvestri GA, Sirajuddin A, Tong BC, Wiener RS, Witt LJ, Donnelly EF. ACR Appropriateness Criteria® Lung Cancer Screening: 2022 Update. Journal of the American College of Radiology : JACR 2023. PMID: 37236754

Jain S, Witt LJ, Ferrante LE. Clin-STAR corner: Recent practice-changing studies at the interface of pulmonary and critical care medicine and geriatrics. Journal of the American Geriatrics Society 2022. PMID: 36536494

Santhosh L, Witt L. Jane (or Dr Doe?) Will Reply to Your Patient Portal Message Now. JAMA network open 2022. PMID: 36197669

Witt LJ, Wroblewski KE, Pinto JM, Wang E, McClintock MK, Dale W, White SR, Press VG, Huisingh-Scheetz M. Beyond the Lung: Geriatric Conditions Afflict Community-Dwelling Older Adults With Self-Reported Chronic Obstructive Pulmonary Disease. Frontiers in medicine 2022. PMID: 35237627

Bischoff KE, Choi S, Su A, Cohen E, O'Riordan DL, Oettel E, Blachman M, Meister S, Zapata C, Lindenfeld P, Calton B, Witt L, Pantilat SZ, Shah RJ. Better Together: A Mixed-Methods Study of Palliative Care Co-Management for Patients with Interstitial Lung Disease. Journal of palliative medicine 2021. PMID: 34115958

Witt LJ, Spacht WA, Carey KA, Arora VM, White SR, Huisingh-Scheetz M, Press VG. Weak Handgrip at Index Admission for Acute Exacerbation of COPD Predicts All-Cause 30-Day Readmission. Frontiers in medicine 2021. PMID: 33898475

O'Leary EM, Tian Y, Nigdelioglu R, Witt LJ, Cetin-Atalay R, Meliton AY, Woods PS, Kimmig LM, Sun KA, Gökalp GA, Mutlu GM, Hamanaka RB. TGF-β Promotes Metabolic Reprogramming in Lung Fibroblasts via mTORC1-dependent ATF4 Activation. American journal of respiratory cell and molecular biology 2020. PMID: 32668192

Farrell TW, Ferrante LE, Brown T, Francis L, Widera E, Rhodes R, Rosen T, Hwang U, Witt LJ, Thothala N, Liu SW, Vitale CA, Braun UK, Stephens C, Saliba D. AGS Position Statement: Resource Allocation Strategies and Age-Related Considerations in the COVID-19 Era and Beyond. Journal of the American Geriatrics Society 2020. PMID: 32374440

Farrell TW, Francis L, Brown T, Ferrante LE, Widera E, Rhodes R, Rosen T, Hwang U, Witt LJ, Thothala N, Liu SW, Vitale CA, Braun UK, Stephens C, Saliba D. Rationing Limited Healthcare Resources in the COVID-19 Era and Beyond: Ethical Considerations Regarding Older Adults. Journal of the American Geriatrics Society 2020. PMID: 32374466

Venado A, Witt LJ, Kallianos K, Wolters PJ. Diaphragmatic Atrophy May Limit Progression of Idiopathic Pulmonary Fibrosis. American journal of respiratory and critical care medicine 2019. PMID: 31825660

Leah J. Witt, Carolyn J. Presley. Respiratory Organ Aging and Cancer. 2020. PMID:

Hamanaka RB, O'Leary EM, Witt LJ, Tian Y, Gökalp GA, Meliton AY, Dulin NO, Mutlu GM. Glutamine Metabolism Is Required for Collagen Protein Synthesis in Lung Fibroblasts. American journal of respiratory cell and molecular biology 2019. PMID: 30973753

Hamanaka RB, Nigdelioglu R, Meliton AY, Tian Y, Witt LJ, O'Leary E, Sun KA, Woods PS, Wu D, Ansbro B, Ard S, Rohde JM, Dulin NO, Guzy RD, Mutlu GM. Inhibition of Phosphoglycerate Dehydrogenase Attenuates Bleomycin-induced Pulmonary Fibrosis. American journal of respiratory cell and molecular biology 2018. PMID: 29019702

Oldham JM, Witt LJ, Adegunsoye A, Chung JH, Lee C, Hsu S, Chen LW, Husain A, Montner S, Vij R, Strek ME, Noth I. N-acetylcysteine exposure is associated with improved survival in anti-nuclear antibody seropositive patients with usual interstitial pneumonia. BMC pulmonary medicine 2018. PMID: 29422061

Leah J. Witt, Carolyn J. Presley. Respiratory Organ Aging and Cancer. Geriatric Oncology 2018. PMID:

Adegunsoye A, Oldham JM, Chung JH, Montner SM, Lee C, Witt LJ, Stahlbaum D, Bermea RS, Chen LW, Hsu S, Husain AN, Noth I, Vij R, Strek ME, Churpek M. Phenotypic Clusters Predict Outcomes in a Longitudinal Interstitial Lung Disease Cohort. Chest 2017. PMID: 28964798

Wu D, Huang RT, Hamanaka RB, Krause M, Oh MJ, Kuo CH, Nigdelioglu R, Meliton AY, Witt L, Dai G, Civelek M, Prabhakar NR, Fang Y, Mutlu GM. HIF-1α is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium. eLife 2017. PMID: 28556776

Adegunsoye A, Oldham JM, Valenzi E, Lee C, Witt LJ, Chen L, Montner S, Chung JH, Noth I, Vij R, Strek ME, Husain AN. Interstitial Pneumonia With Autoimmune Features: Value of Histopathology. Archives of pathology & laboratory medicine 2017. PMID: 28467213

Nigdelioglu R, Hamanaka RB, Meliton AY, O'Leary E, Witt LJ, Cho T, Sun K, Bonham C, Wu D, Woods PS, Husain AN, Wolfgeher D, Dulin NO, Chandel NS, Mutlu GM. Transforming Growth Factor (TGF)-β Promotes de Novo Serine Synthesis for Collagen Production. The Journal of biological chemistry 2016. PMID: 27836973

Oldham JM, Lee C, Valenzi E, Witt LJ, Adegunsoye A, Hsu S, Chen L, Montner S, Chung JH, Noth I, Vij R, Strek ME. Azathioprine response in patients with fibrotic connective tissue disease-associated interstitial lung disease. Respiratory medicine 2016. PMID: 27888985

Daly B, Hantel A, Wroblewski K, Balachandran JS, Chow S, DeBoer R, Fleming GF, Hahn OM, Kline J, Liu H, Patel BK, Verma A, Witt LJ, Fukui M, Kumar A, Howell MD, Polite BN. No Exit: Identifying Avoidable Terminal Oncology Intensive Care Unit Hospitalizations. Journal of oncology practice 2016. PMID: 27601514

Witt LJ, Curran JJ, Strek ME. The Diagnosis and Treatment of Antisynthetase Syndrome. Clinical pulmonary medicine 2016. PMID: 27594777

Oldham JM, Adegunsoye A, Valenzi E, Lee C, Witt L, Chen L, Husain AN, Montner S, Chung JH, Cottin V, Fischer A, Noth I, Vij R, Strek ME. Characterisation of patients with interstitial pneumonia with autoimmune features. The European respiratory journal 2016. PMID: 27103387

Witt LJ, Demchuk C, Curran JJ, Strek ME. Benefit of adjunctive tacrolimus in connective tissue disease-interstitial lung disease. Pulmonary pharmacology & therapeutics 2016. PMID: 26762710

Oldham JM, Ma SF, Martinez FJ, Anstrom KJ, Raghu G, Schwartz DA, Valenzi E, Witt L, Lee C, Vij R, Huang Y, Strek ME, Noth I, IPFnet Investigators. TOLLIP, MUC5B, and the Response to N-Acetylcysteine among Individuals with Idiopathic Pulmonary Fibrosis. American journal of respiratory and critical care medicine 2015. PMID: 26331942

Leah Witt, Carley Demchuk, James Curran, Mary Strek. Safety and Efficacy of Tacrolimus in Connective Tissue Disease-Related Interstitial Lung Disease. CHEST Journal 2013. PMID: