Thiennu Vu, MD, PhD

Education
Post-Doc Fellow/Scholar, 1996 - Medicine, University of California, San Francisco
M.D., 1991 - Medicine, University of California, San Francisco
Ph.D., 1990 - Graduate Division (Cell Biology), University of California, San Francisco
Publications

  1. Zhu W, Shen F, Mao L, Zhan L, Kang S, Sun Z, Nelson J, Zhang R, Zou D, McDougall CM, Lawton MT, Vu TH, Wu Z, Scaria A, Colosi P, Forsayeth J, Su H. Soluble FLT1 Gene Therapy Alleviates Brain Arteriovenous Malformation Severity. Volume 48 of Issue 5. Stroke 2017. PMID: 28325846


  2. Yun EJ, Lorizio W, Seedorf G, Abman SH, Vu TH. VEGF and endothelium-derived retinoic acid regulate lung vascular and alveolar development. Volume 310 of Issue 4. American journal of physiology. Lung cellular and molecular physiology 2015. PMID: 26566904


  3. Hogan BL, Barkauskas CE, Chapman HA, Epstein JA, Jain R, Hsia CC, Niklason L, Calle E, Le A, Randell SH, Rock J, Snitow M, Krummel M, Stripp BR, Vu T, White ES, Whitsett JA, Morrisey EE. Repair and regeneration of the respiratory system: complexity, plasticity, and mechanisms of lung stem cell function. Volume 15 of Issue 2. 2014. PMID: 25105578


  4. Yun EJ, Vu TH. mSmile is necessary for bronchial smooth muscle and alveolar myofibroblast development. Volume 295 of Issue 1. 2011. PMID: 21956870


  5. Harold A. Chapman, Xiaopeng Li, Jonathan P. Alexander, Alexis Brumwell, Walter Lorizio, Kevin Tan, Arnoud Sonnenberg, Ying Wei, Thiennu H. Vu. Integrin a6ß4 identifies an adult distal lung epithelial population with regenerative potential in mice. Journal of Clinical Investigation 2011. PMID:


  6. Chapman HA, Li X, Alexander JP, Brumwell A, Lorizio W, Tan K, Sonnenberg A, Wei Y, Vu TH. Integrin a6ß4 identifies an adult distal lung epithelial population with regenerative potential in mice. Volume 121 of Issue 7. The Journal of clinical investigation 2011. PMID: 21701069


  8. Kim N, Yamamoto H, Pauling MH, Lorizio W, Vu TH. Ablation of lung epithelial cells deregulates FGF-10 expression and impairs lung branching morphogenesis. Volume 292 of Issue 1. 2009. PMID: 19115389


  9. Leung JK, Cases S, Vu TH. P311 functions in an alternative pathway of lipid accumulation that is induced by retinoic acid. Volume 121 of Issue Pt 16. 2008. PMID: 18664493


  10. Yamamoto H, Yun EJ, Gerber HP, Ferrara N, Whitsett JA, Vu TH. Epithelial-vascular cross talk mediated by VEGF-A and HGF signaling directs primary septae formation during distal lung morphogenesis. Volume 308 of Issue 1. 2007. PMID: 17583691


  11. Kim N, Vu TH. Parabronchial smooth muscle cells and alveolar myofibroblasts in lung development. Volume 78 of Issue 1. 2006. PMID: 16622850


  12. Zhao L, Leung JK, Yamamoto H, Goswami S, Kheradmand F, Vu TH. Identification of P311 as a potential gene regulating alveolar generation. Volume 35 of Issue 1. 2006. PMID: 16484684


  13. Hartenstein B, Dittrich BT, Stickens D, Heyer B, Vu TH, Teurich S, Schorpp-Kistner M, Werb Z, Angel P. Epidermal development and wound healing in matrix metalloproteinase 13-deficient mice. Volume 126 of Issue 2. 2006. PMID: 16374453


  14. Zhao L, Wang K, Ferrara N, Vu TH. Vascular endothelial growth factor co-ordinates proper development of lung epithelium and vasculature. Volume 122 of Issue 7-8. 2005. PMID: 15927453


  15. Wang K, Yamamoto H, Chin JR, Werb Z, Vu TH. Epidermal growth factor receptor-deficient mice have delayed primary endochondral ossification because of defective osteoclast recruitment. Volume 279 of Issue 51. The Journal of biological chemistry 2004. PMID: 15456762


  16. Pauling MH, Vu TH. Mechanisms and regulation of lung vascular development. Volume 64. 2004. PMID: 15563945


  17. Vu TH, Alemayehu Y, Werb Z. New insights into saccular development and vascular formation in lung allografts under the renal capsule. Volume 120 of Issue 3. 2003. PMID: 12591600


  18. Vu TH. Don't mess with the matrix. Volume 28 of Issue 3. 2001. PMID: 11431682


  19. Engsig MT, Chen QJ, Vu TH, Pedersen AC, Therkidsen B, Lund LR, Henriksen K, Lenhard T, Foged NT, Werb Z, Delaissé JM. Matrix metalloproteinase 9 and vascular endothelial growth factor are essential for osteoclast recruitment into developing long bones. Volume 151 of Issue 4. 2000. PMID: 11076971


  20. Bergers G, Brekken R, McMahon G, Vu TH, Itoh T, Tamaki K, Tanzawa K, Thorpe P, Itohara S, Werb Z, Hanahan D. Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Volume 2 of Issue 10. 2000. PMID: 11025665


  21. Mark D. Sternlicht, Lisa M. Coussens, Thiennu H. Vu, Zena Werb. Biology and Regulation of the Matrix Metalloproteinases. Matrix Metalloproteinase Inhibitors in Cancer Therapy 2000. PMID:


  22. Vu TH, Werb Z. Matrix metalloproteinases: effectors of development and normal physiology. Volume 14 of Issue 17. 2000. PMID: 10970876


  23. Delaissé JM, Engsig MT, Everts V, del Carmen Ovejero M, Ferreras M, Lund L, Vu TH, Werb Z, Winding B, Lochter A, Karsdal MA, Troen T, Kirkegaard T, Lenhard T, Heegaard AM, Neff L, Baron R, Foged NT. Proteinases in bone resorption: obvious and less obvious roles. Volume 291 of Issue 2. 2000. PMID: 10675725


  24. Gerber HP, Vu TH, Ryan AM, Kowalski J, Werb Z, Ferrara N. VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation. Volume 5 of Issue 6. Nature medicine 1999. PMID: 10371499


  25. Werb Z, Vu TH, Rinkenberger JL, Coussens LM. Matrix-degrading proteases and angiogenesis during development and tumor formation. Volume 107 of Issue 1. 1999. PMID: 10190275


  26. Liu Z, Shipley JM, Vu TH, Zhou X, Diaz LA, Werb Z, Senior RM. Gelatinase B-deficient mice are resistant to experimental bullous pemphigoid. Volume 188 of Issue 3. 1998. PMID: 9687525


  27. Vu TH, Shipley JM, Bergers G, Berger JE, Helms JA, Hanahan D, Shapiro SD, Senior RM, Werb Z. MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes. Volume 93 of Issue 3. 1998. PMID: 9590175


  28. Thiennu H. Vu, Zena Werb. Gelatinase B: Structure, Regulation, and Function. Matrix Metalloproteinases 1998. PMID: