Cystic Fibrosis Clinical Trials

Mucus Study ("MUCGAL")


The purpose of this study is to investigate how abnormal mucus forms in diseases of the airways such as asthma and cystic fibrosis.

Detailed Description

The study protocol involves collection of samples of induced sputum from healthy controls and patients with asthma and cystic fibrosis. Induced sputum is sputum that is coughed up when a solution of salty water is inhaled. The study protocol involves multiple visits for collection of the induced sputum - usually the visit number is between two and 5 but it can be as high as 10. By examining the biochemical and biophysical properties of the sputum samples from different patient groups and also the effects of drugs and chemicals on the sputum after it is collected, we can infer mechanism of disease that may be helpful in developing drugs to treat abnormal mucus.

Please call 1-866-2-INHALE for more information on the MUCGAL study.